Synthesis of indolo[2,3-c]coumarins and indolo[2,3-c]quinolinones via microwave-assisted base-free intramolecular cross dehydrogenative coupling
文献类型：期刊论文
| 作者 | Gu, Chang-Xue1,2; Chen, Wen-Wen1 ; Xu, Bin2; Xu, Ming-Hua1
|
| 刊名 | TETRAHEDRON
 |
| 出版日期 | 2019-03-22 |
| 卷号 | 75期号:12页码:1605-1611 |
| 关键词 | Indolo[2,3-c]coumarin Indolo[2,3-c]quinolinone Palladium Cross dehydrogenative coupling Microwave-assisted synthesis Fused polyheterocycles |
| ISSN号 | 0040-4020 |
| DOI | 10.1016/j.tet.2018.11.066 |
| 通讯作者 | Chen, Wen-Wen(wenwen@simm.ac.cn) ; Xu, Ming-Hua(xumh@simm.ac.cn) |
| 英文摘要 | A microwave-assisted base-free intramolecular cross dehydrogenative coupling (CDC) of 3-aniline substituted coumarins and quinolinones have been developed. A broad range of indolo[2,3-c]coumarins and indolo[2,3-c]quinolinones can be easily afforded in good to high yields (up to 93%) under palladium catalysis. The method is among the most straightforward and convenient ways to access these fused polyheterocycles. (C) 2018 Elsevier Ltd. All rights reserved. |
| WOS关键词 | RESISTANCE REVERSAL ACTIVITY ; MULTIDRUG-RESISTANCE ; LAMELLARIN-D ; BENZOPYRANONES ; CONSTRUCTION ; ALKALOIDS ; NINGALINS ; ANALOGS ; ACCESS |
| 资助项目 | National Natural Science Foundation of China[21472205] ; National Natural Science Foundation of China[81521005] ; National Natural Science Foundation of China[21325209] ; Shanghai Municipal Committee of Science and Technology[18ZR1447600] ; SA-SIBS Scholarship Program |
| WOS研究方向 | Chemistry |
| 语种 | 英语 |
| WOS记录号 | WOS:000462418900006 |
| 出版者 | PERGAMON-ELSEVIER SCIENCE LTD |
| 源URL | [http://119.78.100.183/handle/2S10ELR8/290190]  |
| 专题 | 新药研究国家重点实验室 |
| 通讯作者 | Chen, Wen-Wen; Xu, Ming-Hua |
| 作者单位 | 1.Chinese Acad Sci, Shanghai Inst Mat Med, State Key Lab Drug Res, 555 Zuchongzhi Rd, Shanghai 201203, Peoples R China 2.Shanghai Univ, Innovat Drug Res Ctr, Dept Chem, Shanghai 200444, Peoples R China |
| 推荐引用方式 GB/T 7714 | Gu, Chang-Xue,Chen, Wen-Wen,Xu, Bin,et al. Synthesis of indolo[2,3-c]coumarins and indolo[2,3-c]quinolinones via microwave-assisted base-free intramolecular cross dehydrogenative coupling[J]. TETRAHEDRON,2019,75(12):1605-1611. |
| APA | Gu, Chang-Xue,Chen, Wen-Wen,Xu, Bin,&Xu, Ming-Hua.(2019).Synthesis of indolo[2,3-c]coumarins and indolo[2,3-c]quinolinones via microwave-assisted base-free intramolecular cross dehydrogenative coupling.TETRAHEDRON,75(12),1605-1611. |
| MLA | Gu, Chang-Xue,et al."Synthesis of indolo[2,3-c]coumarins and indolo[2,3-c]quinolinones via microwave-assisted base-free intramolecular cross dehydrogenative coupling".TETRAHEDRON 75.12(2019):1605-1611. |
入库方式： OAI收割
来源：上海药物研究所
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