Single-molecular detection of polysaccharides with chemically-modified nanopores
文献类型：会议论文
| 作者 | Cai, Yao2; Liang, Liyuan1 ; Wang, Sen1; Wang, Deqiang1; Cui, Hongliang1
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| 出版日期 | 2019 |
| 会议日期 | August 4, 2019 - August 8, 2019 |
| 会议地点 | Zhenjiang, China |
| DOI | 10.1109/3M-NANO46308.2019.8947361 |
| 页码 | 257-260 |
| 英文摘要 | Carbohydrate is an important energy source for human body. Among them, saccharides are the main energy for all living organisms to maintain their life activities, and hold some special physiological activities compared with other nutrients. In consideration of their significance in biological process and structural intricacy, a new precise and reliable technique for their structure identification and discrimination is highly desired. In this work, covalently-modified solid-state nanopores (SSN) have been employed for the detection of polysaccharides with a sample concentration of 5 ng/μL under 150 mV of bias, the experimental findings suggested that polysaccharides have different perforation behavior in chemically-modified nanopores compared with that in bare ones due to specific interactions between polysaccharides and modified inner pore surface, in addition, oligo- and polysaccharides exhibited evident distinct translocation characteristics. The results highlight the applicability of SSN approach for the determination of polysaccharides with high accuracy. © 2019 IEEE. |
| 会议录 | 9th IEEE International Conference on Manipulation, Manufacturing and Measurement on the Nanoscale, 3M-NANO 2019
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| 语种 | 英语 |
| 源URL | [http://119.78.100.138/handle/2HOD01W0/9791]  |
| 专题 | 中国科学院重庆绿色智能技术研究院 |
| 作者单位 | 1.University of Chinese Academy of Science, Chongqing Key Laboratory of Multi-scale Manufacturing Technology, Chongqing Institute of Green and Intelligent Technology, Chongqing, China 2.Jilin University, College of Instrumentation and Electrical Engineering, Changchun, China; |
| 推荐引用方式 GB/T 7714 | Cai, Yao,Liang, Liyuan,Wang, Sen,et al. Single-molecular detection of polysaccharides with chemically-modified nanopores[C]. 见:. Zhenjiang, China. August 4, 2019 - August 8, 2019. |
入库方式： OAI收割
来源：重庆绿色智能技术研究院
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