Cell Behavior on 3D Ti-6Al-4 v Scaffolds with Different Porosities
文献类型：期刊论文
| 作者 | Liu, Jie1; Jin, Feng1; Zheng, Mei-Ling1; Wang, Sen4 ; Fan, Shu-Qian4; Li, Peng2; Duan, Xuan-Ming3
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| 刊名 | ACS Applied Bio Materials
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| 出版日期 | 2019 |
| 卷号 | 2期号:2页码:697-703 |
| DOI | 10.1021/acsabm.8b00550 |
| 英文摘要 | Porous titanium (Ti) and its alloys fabricated by additive manufacturing (AM) techniques have attractive potential for dental and bone defect repair fields. Understanding the relationship between cells and the surface of the as-built three-dimensional (3D) scaffold interactions is not only necessary for tissue engineering but also promising for improving the fabrication process in the manufacture of artificial implants by AM technology. In this study, we have aimed to investigate the cell behavior including adhesion and proliferation of fibroblasts (L929) on Ti-6Al-4 V scaffolds fabricated by the electron beam melting method. The porosities of Ti-6Al-4 V scaffolds are 0% (compact), 60%, and 70%, respectively. Different cell behaviors have been observed from all of the specimens after 4 and 8 days of cell incubation. The present result indicates that, besides the surface roughness, the surface topography of specimens should also be taken into consideration to investigate the interaction between implants and cells. Therefore, this study would provide several possibilities for improving the osteointegration functions of the manufactured porous metallic implants in orthopedic and dental applications. Copyright © 2019 American Chemical Society. |
| 电子版国际标准刊号 | 25766422 |
| 语种 | 英语 |
| 源URL | [http://119.78.100.138/handle/2HOD01W0/9815]  |
| 专题 | 中国科学院重庆绿色智能技术研究院 |
| 作者单位 | 1.Lab. of Organ. NanoPhotonics and CAS Key Lab. of Bio-Inspired Materials and Interfacial Science, Technical Institute of Physics and Chemistry, Chinese Academy of Sciences, No. 29 Zhongguancun East Road, Beijing; 100190, China; 2.Department of Orthopedics, Chinese PLA General Hospital, Beijing; 100853, China 3.Guangdong Provincial Key Laboratory of Optical Fiber Sensing and Communications, Institute of Photonics Technology, Jinan University, Guangzhou; 510632, China; 4.Chongqing Institute of Green and Intelligent Technology, Chinese Academy of Sciences, No. 266 Fangzheng Ave, Shuitu Technology Development Zone, Beibei District, Chongqing; 400714, China; |
| 推荐引用方式 GB/T 7714 | Liu, Jie,Jin, Feng,Zheng, Mei-Ling,et al. Cell Behavior on 3D Ti-6Al-4 v Scaffolds with Different Porosities[J]. ACS Applied Bio Materials,2019,2(2):697-703. |
| APA | Liu, Jie.,Jin, Feng.,Zheng, Mei-Ling.,Wang, Sen.,Fan, Shu-Qian.,...&Duan, Xuan-Ming.(2019).Cell Behavior on 3D Ti-6Al-4 v Scaffolds with Different Porosities.ACS Applied Bio Materials,2(2),697-703. |
| MLA | Liu, Jie,et al."Cell Behavior on 3D Ti-6Al-4 v Scaffolds with Different Porosities".ACS Applied Bio Materials 2.2(2019):697-703. |
入库方式： OAI收割
来源：重庆绿色智能技术研究院
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