On the flow characteristics in different carotid arteries
文献类型：期刊论文
| 作者 | Chen Y(陈与)3,4; Yang XL(杨晓雷)2,4 ; Iskander AJ1; Wang P3
|
| 刊名 | PHYSICS OF FLUIDS
 |
| 出版日期 | 2020-10-01 |
| 卷号 | 32期号:10页码:17 |
| ISSN号 | 1070-6631 |
| DOI | 10.1063/5.0022092 |
| 通讯作者 | Yang, Xiaolei(xyang@imech.ac.cn) |
| 英文摘要 | Hemodynamics plays an important role in the cause of atherosclerotic disease. In this work, we simulated the flow fields in six human carotids using the sharp-interface immersed boundary method. We compare the axial velocity, the secondary flow, the vortex structures, the area with reversed flows, and the standard deviation of velocity fluctuations for different carotids. The computed results show similarities among different carotids for the overall pattern of different flow characteristics. More importantly, differences are observed in terms of the details of the area of the reversed flow region, the size and shape of the region dominated by reversed flows, and the length of time with reversed flow or dominated by secondary flows, which are strongly correlated with the formation of plaques. Further analysis shows that patient-specific features of the carotid geometry, e.g., the flare and proximal curvature of the carotid, have significant effects on these flow characteristics. This suggests that a patient-specific program is needed for the prevention and treatment of atherosclerosis. |
| 分类号 | 一类/力学重要期刊 |
| WOS关键词 | WALL SHEAR-STRESS ; BLOOD-FLOW ; BIFURCATION GEOMETRY ; NUMERICAL-SIMULATION ; PULSATILE FLOW ; WAVE-FORMS ; MODEL ; ATHEROSCLEROSIS ; ASSOCIATION ; PREDICTOR |
| 资助项目 | NSFC Basic Science Center Program for Multiscale Problems in Nonlinear Mechanics[11988102] |
| WOS研究方向 | Mechanics ; Physics |
| 语种 | 英语 |
| WOS记录号 | WOS:000582121800001 |
| 资助机构 | NSFC Basic Science Center Program for Multiscale Problems in Nonlinear Mechanics |
| 其他责任者 | Yang, Xiaolei |
| 源URL | [http://dspace.imech.ac.cn/handle/311007/85387]  |
| 专题 | 力学研究所_非线性力学国家重点实验室 |
| 作者单位 | 1.Westchester Med Ctr, Dept Anesthesiol, 100 Woods Rd, Valhalla, NY 10595 USA 2.Univ Chinese Acad Sci, Sch Engn Sci, Beijing 100049, Peoples R China; 3.Lanzhou Univ, Dept Mech, Lanzhou 730000, Peoples R China; 4.Chinese Acad Sci, Inst Mech, State Key Lab Nonlinear Mech, Beijing 100190, Peoples R China; |
| 推荐引用方式 GB/T 7714 | Chen Y,Yang XL,Iskander AJ,et al. On the flow characteristics in different carotid arteries[J]. PHYSICS OF FLUIDS,2020,32(10):17. |
| APA | 陈与,杨晓雷,Iskander AJ,&Wang P.(2020).On the flow characteristics in different carotid arteries.PHYSICS OF FLUIDS,32(10),17. |
| MLA | 陈与,et al."On the flow characteristics in different carotid arteries".PHYSICS OF FLUIDS 32.10(2020):17. |
入库方式： OAI收割
来源：力学研究所
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