Highly sensitive turn-on detection of mercury(II) in aqueous solutions and live cells with a chemosensor based on tyrosine
文献类型：期刊论文
| 作者 | Wang, Peng; An, Yong; Wu, Jiang |
| 刊名 | SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY
 |
| 出版日期 | 2020 |
| 卷号 | 230 |
| 关键词 | Tyrosine Fluorescent chemosensor Hg(II) Aqueous solutions Cells imaging |
| 英文摘要 | Herein, we reported a novel fluorescent chemosensor (DY) based on dansyl group and tyrosine by solid phase peptide synthesis (SPPS) for the detection of mercury(11) ions with excellent selectivity among 17 different metal ions. As designed. DY exhibited a sensitive fluorescence "turn-on" response to Hg2+ with low detection limits of 22.65 nM. A stoichiometric ratio (2: 1) of chemosensor DY and Hg2+ ions was determined by a Job's plot, fluorescent titration and the ESI-MS spectra. Especially, the reversible of DY-Hg with EDTA establishes the reuse of DY, and the circulation effect was very good. Furthermore, the wide pH range of 6-10 makes it capable of application in biological systems. Moreover, DY has been successfully applied to the detection of Hg2+ ions and EDTA in living HeLa and HK2 cells based on low cytotoxicity and good membrane permeability. (C) 2020 Elsevier B.V. All rights reserved. |
| 源URL | [http://210.75.249.4/handle/363003/60361]  |
| 专题 | 西北高原生物研究所_中国科学院西北高原生物研究所 |
| 推荐引用方式 GB/T 7714 | Wang, Peng,An, Yong,Wu, Jiang. Highly sensitive turn-on detection of mercury(II) in aqueous solutions and live cells with a chemosensor based on tyrosine[J]. SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY,2020,230. |
| APA | Wang, Peng,An, Yong,&Wu, Jiang.(2020).Highly sensitive turn-on detection of mercury(II) in aqueous solutions and live cells with a chemosensor based on tyrosine.SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY,230. |
| MLA | Wang, Peng,et al."Highly sensitive turn-on detection of mercury(II) in aqueous solutions and live cells with a chemosensor based on tyrosine".SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY 230(2020). |
入库方式： OAI收割
来源：西北高原生物研究所
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