Mesoporous superparamagnetic cobalt ferrite nanoclusters: Synthesis, characterization and application in drug delivery
文献类型：期刊论文
| 作者 | Shi, Zhimin; Zeng, Yingzhe; Chen, Xin; Zhou, Fei; Zheng, Liyun; Wang, Guangshuo; Gao, Jie; Ma, Yingying; Zheng, Lianhong; Fu, Bin |
| 刊名 | JOURNAL OF MAGNETISM AND MAGNETIC MATERIALS
 |
| 出版日期 | 2020 |
| 卷号 | 498 |
| 关键词 | Cobalt ferrite L-Arginine Nanoclusters Mesoporous Superparamagnetic Drug delivery |
| 英文摘要 | In this contribution, an amino acid of L-Arginine coated cobalt ferrite (CoFe2O4) nanoclusters with mesoporous structure were synthesized via a facile solvothermal strategy. The morphology, structure and properties of bare CoFe2O4 and L-Arg-coated CoFe2O4 nanoclusters were characterized in detail by SEM, TEM, XRD, XPS, TGA, BET and SQUID. It was found that these products exhibited a well-defined clusters-like morphology and a uniform size distribution with an average diameter of 103.6 nm. The as-prepared superparamagnetic CoFe2O4 nanoclusters with mesoporous structure and negligible cytotoxicity could be utilized as an effective drug delivery for doxorubicin hydrochloride (DOX). The drug loading capacity and the release behavior in vitro of DOX from L-Arg-coated CoFe2O4 nanoclusters at different pH values (4.0 and 7.4) were investigated. The results showed that the developed drug delivery system exhibited a high drug loading capacity and a pH-sensitive drug release behavior. |
| 源URL | [http://210.75.249.4/handle/363003/60386]  |
| 专题 | 西北高原生物研究所_中国科学院西北高原生物研究所 |
| 推荐引用方式 GB/T 7714 | Shi, Zhimin,Zeng, Yingzhe,Chen, Xin,et al. Mesoporous superparamagnetic cobalt ferrite nanoclusters: Synthesis, characterization and application in drug delivery[J]. JOURNAL OF MAGNETISM AND MAGNETIC MATERIALS,2020,498. |
| APA | Shi, Zhimin.,Zeng, Yingzhe.,Chen, Xin.,Zhou, Fei.,Zheng, Liyun.,...&Yu, Ruitao.(2020).Mesoporous superparamagnetic cobalt ferrite nanoclusters: Synthesis, characterization and application in drug delivery.JOURNAL OF MAGNETISM AND MAGNETIC MATERIALS,498. |
| MLA | Shi, Zhimin,et al."Mesoporous superparamagnetic cobalt ferrite nanoclusters: Synthesis, characterization and application in drug delivery".JOURNAL OF MAGNETISM AND MAGNETIC MATERIALS 498(2020). |
入库方式： OAI收割
来源：西北高原生物研究所
浏览0
下载0
收藏0
其他版本
除非特别说明，本系统中所有内容都受版权保护，并保留所有权利。