TBAF-Catalyzed Cyclization Reactions of o-(Alkynyl)phenyl Propargyl Alcohols with Malonate Esters: A Possible Cation-pi Interaction as The Activation Approach
文献类型：期刊论文
| 作者 | Zhao, Yulei; Guo, Xuqiang; Wang, Zongkang; Shen, Duyi; Chen, Tingting; Wu, Nan; Yan, Shina; You, Jinmao
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| 刊名 | EUROPEAN JOURNAL OF ORGANIC CHEMISTRY
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| 出版日期 | 2020 |
| 卷号 | 2020期号:8 |
| 关键词 | TBAF Cation-pi interaction Dihydroisobenzofuran Malonate ester Cyclization reaction |
| 英文摘要 | An efficient method has been devised for the synthesis of dihydroisobenzofuran derivatives through the reaction of in situ generated ynones with potentially C-nucleophilic malonate esters. All the products are capable to be prepared by applying the tandem strategy at room temperature. The reaction was realized through a combination of the pivotal TBAF-catalyzed conjugate addition and selective O-nucleophilic cyclization. As revealed by the control experiments, both the basicity of fluoride anion and ammonium cation-pi interaction with alkyne unit might play crucial roles in the cyclization reaction. |
| 源URL | [http://210.75.249.4/handle/363003/60409]  |
| 专题 | 西北高原生物研究所_中国科学院西北高原生物研究所 |
| 推荐引用方式 GB/T 7714 | Zhao, Yulei,Guo, Xuqiang,Wang, Zongkang,et al. TBAF-Catalyzed Cyclization Reactions of o-(Alkynyl)phenyl Propargyl Alcohols with Malonate Esters: A Possible Cation-pi Interaction as The Activation Approach[J]. EUROPEAN JOURNAL OF ORGANIC CHEMISTRY,2020,2020(8). |
| APA | Zhao, Yulei.,Guo, Xuqiang.,Wang, Zongkang.,Shen, Duyi.,Chen, Tingting.,...&You, Jinmao.(2020).TBAF-Catalyzed Cyclization Reactions of o-(Alkynyl)phenyl Propargyl Alcohols with Malonate Esters: A Possible Cation-pi Interaction as The Activation Approach.EUROPEAN JOURNAL OF ORGANIC CHEMISTRY,2020(8). |
| MLA | Zhao, Yulei,et al."TBAF-Catalyzed Cyclization Reactions of o-(Alkynyl)phenyl Propargyl Alcohols with Malonate Esters: A Possible Cation-pi Interaction as The Activation Approach".EUROPEAN JOURNAL OF ORGANIC CHEMISTRY 2020.8(2020). |
入库方式： OAI收割
来源：西北高原生物研究所
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