Traceability of Geographical Origin in Gentiana straminea by UPLC-Q Exactive Mass and Multivariate Analyses
文献类型：期刊论文
| 作者 | Pan, Zheng; Xiong, Feng ; Chen, Yi-Long; Wan, Guo-Guo; Zhang, Yi; Chen, Zhi-Wei; Cao, Wen-Fu; Zhou, Guo-Ying
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| 刊名 | MOLECULES
 |
| 出版日期 | 2019 |
| 卷号 | 24期号:24 |
| 关键词 | Gentiana straminea geographical origin UPLC-Q exactive mass metabolomics multivariate analysis |
| 英文摘要 | The root of Gentiana straminea Maxim. (Gentianaceae), is officially listed as "Qin-Jiao" in the Chinese Pharmacopoeia for the treatment of rheumatic arthritis, icteric hepatitis, constipation, pain, and hypertension. To establish the geographical origin traceability in G. straminea, its chemical profiles were determined by a UPLC-Q exactive mass spectrometer, from which 43 compounds were identified by comparing retention times and mass spectrometry. Meanwhile, a pair of isomers (loganin and secologanol) was identified by mass spectrometry based on their fragmentation pathway. A total of 42 samples from difference habitats were determined by an UPLC-Q exactive mass spectrometer and the data were assayed with multivariate statistical analysis. Eight characteristic compounds were identified to determine the geographical origin of the herb. To estimate the key characteristic markers associated with pharmacological function, the inhibiting activities of nitric oxide (NO) production in lipopolysaccharide (LPS)-induced macrophages were examined. This finding is crucial in realizing the determination of botanical origin and evaluating the quality of G. straminea. |
| 源URL | [http://210.75.249.4/handle/363003/60483]  |
| 专题 | 西北高原生物研究所_中国科学院西北高原生物研究所 |
| 推荐引用方式 GB/T 7714 | Pan, Zheng,Xiong, Feng,Chen, Yi-Long,et al. Traceability of Geographical Origin in Gentiana straminea by UPLC-Q Exactive Mass and Multivariate Analyses[J]. MOLECULES,2019,24(24). |
| APA | Pan, Zheng.,Xiong, Feng.,Chen, Yi-Long.,Wan, Guo-Guo.,Zhang, Yi.,...&Zhou, Guo-Ying.(2019).Traceability of Geographical Origin in Gentiana straminea by UPLC-Q Exactive Mass and Multivariate Analyses.MOLECULES,24(24). |
| MLA | Pan, Zheng,et al."Traceability of Geographical Origin in Gentiana straminea by UPLC-Q Exactive Mass and Multivariate Analyses".MOLECULES 24.24(2019). |
入库方式： OAI收割
来源：西北高原生物研究所
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