Integrative analysis of APOL3 gene CNV for adult cattle stature
文献类型：期刊论文
| 作者 | Peng, Shu-Jun; Cao, Xiu-Kai; Dong, Dong; Liu, Mei; Hao, Dan; Shen, Xue-Mei; Huang, Yong-Zhen; Lei, Chu-Zhao; Ma, Yun; Bai, Yue-Yu |
| 刊名 | ANIMAL BIOTECHNOLOGY
 |
| 出版日期 | 2019 |
| 卷号 | 31期号:5 |
| 关键词 | APOL3 CNV cattle stature animal breeding |
| 英文摘要 | Copy number variations (CNVs) have been identified as another important structural variation of genome. In recent years, a large amount of CNVRs have been identified in humans and animals. However, association and dosage effects studies of CNVs are very limited. Apolipoprotein L3 (APOL3) gene plays a central role in modulating gene transcription and is located within a CNVR that encompasses quantitative trait locis (QTLs) for economic traits like meat quality. Herein, we analyzed the CNV polymorphism of APOL3 in 421 individuals from five distinct cattle breeds, and then correlated their genotypes with growth traits. Association analysis revealed that the APOL3 CNV was significantly associated with hip height and cannon circumference of Xianan (XN) cattle (P < .01), and visibly associated with body slanting length and hucklebone width of Pinan (PN) cattle (P < .05). Overall, the data provide evidence for the functional role of APOL3 CNV and a basis for future applications in cattle breeding. |
| 源URL | [http://210.75.249.4/handle/363003/60518]  |
| 专题 | 西北高原生物研究所_中国科学院西北高原生物研究所 |
| 推荐引用方式 GB/T 7714 | Peng, Shu-Jun,Cao, Xiu-Kai,Dong, Dong,et al. Integrative analysis of APOL3 gene CNV for adult cattle stature[J]. ANIMAL BIOTECHNOLOGY,2019,31(5). |
| APA | Peng, Shu-Jun.,Cao, Xiu-Kai.,Dong, Dong.,Liu, Mei.,Hao, Dan.,...&Chen, Hong.(2019).Integrative analysis of APOL3 gene CNV for adult cattle stature.ANIMAL BIOTECHNOLOGY,31(5). |
| MLA | Peng, Shu-Jun,et al."Integrative analysis of APOL3 gene CNV for adult cattle stature".ANIMAL BIOTECHNOLOGY 31.5(2019). |
入库方式： OAI收割
来源：西北高原生物研究所
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