Label-free ferrule-top optical fiber micro-cantilever biosensor
文献类型：期刊论文
| 作者 | Li, J.1,2; Zhou, Y. X.3; Guo, Y. X.2; Wang, G. Y.1; Maier, R. R. J.4; Hand, D. P.4; MacPherson, W. N.4 |
| 刊名 | SENSORS AND ACTUATORS A-PHYSICAL
 |
| 出版日期 | 2018-09-01 |
| 卷号 | 280页码:505-512 |
| 关键词 | Ferrule-top cantilever Label-free Bio-sensing ns-Laser machining |
| ISSN号 | 0924-4247 |
| DOI | 10.1016/j.sna.2018.07.014 |
| 通讯作者 | Li, J.(ljsiom@aiofm.ac.cn) |
| 英文摘要 | Micro-cantilever sensors have shown great promise in a wide range of applications including chemical medical and biological sensing. However, many of these devices are based upon a sensor 'chip' that requires careful alignment between the cantilever and the read-out system, which can be challenging. Furthermore, optical interrogation typically involves a bulky free-space system. Optical fiber addressed cantilevers have been reported previously in the literature and in this paper we propose techniques to design and fabricate polymer micro-cantilevers onto the end of standard single mode fibers using ns-laser machining. The cantilever will deflect and thereby observing biological binding between species of interests and activated cantilevers. Proof-of-concept experiments demonstrate that the sensor is capable of detecting Listeria food pathogen concentrations with a minimum level of less than 10(5)cfu/ml. (C) 2018 Elsevier B.V. All rights reserved. |
| WOS关键词 | SENSORS ; ARRAY ; MICROCANTILEVERS ; TECHNOLOGY ; MONOLAYERS ; GOLD |
| 资助项目 | Innovative Manufacturing Research Centre under EPSRC[EP/F02553X/1] ; Renishaw plc. |
| WOS研究方向 | Engineering ; Instruments & Instrumentation |
| 语种 | 英语 |
| WOS记录号 | WOS:000447097200062 |
| 出版者 | ELSEVIER SCIENCE SA |
| 资助机构 | Innovative Manufacturing Research Centre under EPSRC ; Innovative Manufacturing Research Centre under EPSRC ; Innovative Manufacturing Research Centre under EPSRC ; Innovative Manufacturing Research Centre under EPSRC ; Innovative Manufacturing Research Centre under EPSRC ; Innovative Manufacturing Research Centre under EPSRC ; Innovative Manufacturing Research Centre under EPSRC ; Innovative Manufacturing Research Centre under EPSRC ; Renishaw plc. ; Renishaw plc. ; Renishaw plc. ; Renishaw plc. ; Renishaw plc. ; Renishaw plc. ; Renishaw plc. ; Renishaw plc. ; Innovative Manufacturing Research Centre under EPSRC ; Innovative Manufacturing Research Centre under EPSRC ; Innovative Manufacturing Research Centre under EPSRC ; Innovative Manufacturing Research Centre under EPSRC ; Innovative Manufacturing Research Centre under EPSRC ; Innovative Manufacturing Research Centre under EPSRC ; Innovative Manufacturing Research Centre under EPSRC ; Innovative Manufacturing Research Centre under EPSRC ; Renishaw plc. ; Renishaw plc. ; Renishaw plc. ; Renishaw plc. ; Renishaw plc. ; Renishaw plc. ; Renishaw plc. ; Renishaw plc. |
| 源URL | [http://ir.hfcas.ac.cn:8080/handle/334002/39426]  |
| 专题 | 中国科学院合肥物质科学研究院 |
| 通讯作者 | Li, J. |
| 作者单位 | 1.Chinese Acad Sci, Anhui Inst Opt & Fine Mech, Hefei 230031, Anhui, Peoples R China 2.Xian Univ Sci & Technol, Sch Safety Engn, Xian 710054, Shaanxi, Peoples R China 3.Senboll Biotechnol Co Ltd, Shenzhen 518118, Peoples R China 4.Heriot Watt Univ, Inst Photon & Quantum Sci, Edinburgh, Midlothian, Scotland |
| 推荐引用方式 GB/T 7714 | Li, J.,Zhou, Y. X.,Guo, Y. X.,et al. Label-free ferrule-top optical fiber micro-cantilever biosensor[J]. SENSORS AND ACTUATORS A-PHYSICAL,2018,280:505-512. |
| APA | Li, J..,Zhou, Y. X..,Guo, Y. X..,Wang, G. Y..,Maier, R. R. J..,...&MacPherson, W. N..(2018).Label-free ferrule-top optical fiber micro-cantilever biosensor.SENSORS AND ACTUATORS A-PHYSICAL,280,505-512. |
| MLA | Li, J.,et al."Label-free ferrule-top optical fiber micro-cantilever biosensor".SENSORS AND ACTUATORS A-PHYSICAL 280(2018):505-512. |
入库方式： OAI收割
来源：合肥物质科学研究院
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