Modulated lower hybrid waves, are injected into the Experimental Advanced Superconducting Tokamak (EAST), to investigate the modulated evolutions of pedestal structure and unstable edge-localized modes (ELMs). The spectrum patterns of D-alpha show that the ELM amplitude only slightly decreases while the ELM frequency becomes almost 3-5 times larger as the lower hybrid radio frequency (LHRF) jumps into the lower power level. Pedestal structure analysis indicates that higher LHRF power injection can increase the plasma stored energy and core plasma parameters, accompanying with the pedestal shift and gradient increase. Ion saturation contour current plots suggest that LHRF power can deposit in the plasma edge region to profoundly change the three-dimensional (3D) magnetic topology, similarly to the effect of resonant magnetic perturbations (RMPs), by inducing the helical current filaments (HCFs) following along the magnetic field lines in the scrape-off layer (SOL), which may cause the density pump-out effect by increasing the radial plasma transport. The modulated higher temperature and lower density of pedestal top-values can reduce the pedestal collisionality, which will strongly increase the bootstrap current density and gradually shift the Peeling-Ballooning mode (PBM) boundary. ELITE code stability analysis indicates that LHRF injection can lead to the relatively unstable ELMs with a higher pedestal gradient, simultaneously accompanying with the normalized pressure gradient and edge bootstrap current density increase. All of these results imply that there is a significant correlation between the ELM behavior and pedestal structure modulation because of LHRF dissipation at the plasma edge for the unstable ELM modulated case.