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Methodology of dose calculation for external beam radiation combined with high dose rate brachytherapy in the era of 3-dimensional treatment planning system

文献类型：期刊论文

作者Wang, Fangzheng1,2,3,4,5; Jiang, Chuner1,6; Liu, Tongxin1,2,3,4,5; Sun, Quanquan1,2,3,4; Ye, Zhimin1,2,3,4; Shi, Kaiyuan1,7; Wu, Peng1,8; Qin, Weifeng1,2,3,4,5; Fu, Zhenfu1,2,3,4,5; Jiang, Yangming9
刊名MEDICINE
出版日期2020-07-17
卷号99
关键词American Association of Physicists in Medicine Task Group 43 brachytherapy combined dose distribution external beam radiotherapy
ISSN号0025-7974
DOI10.1097/MD.0000000000020760
通讯作者Wang, Fangzheng(wangfz76@126.com) ; Jiang, Yangming(jym_wm@126.com)
英文摘要Intracavitary application of brachytherapy (BT) sources followed by external beam radiation is essential for the local treatment of carcinoma of the cervix, postate, and nasopharynx. Dose distribution of external beam radiation plus BT can be challenging for the planning system because of their dose calculation by 2 different treatment planning system (TPS). The aims of this study were to introduce a novel iterative method of dose calculation preformed in the Pinnacle plan and evaluate a combined dose distribution for external beam radiation and BT. Because it is often the goal of the planner to produce plan with uniform dose throughout the target volume and normal tissue, we present an Iridium-192 calculation program using American Association of Physicists in Medicine Task Group 43 formula and export it to other commercialized TPS though the combined dose distribution of external beam radiation and BT can be shown. To illustrate such an improved procedure, we present the treatment plans of 2 patients treated with external beam radiation plus BT. Dose distribution of the single BT source were calculated with the Plato post loading TPS and the program model, and the results of 2 methods were similar. A nasopharyngeal case and a cervical case were shown in Pinnacle with this program. The total dose distribution of BT combined with EBRT was showed in compute tomography images. And the corresponding dose volume histogram figures could be displayed correctly in Pinnacle TPS. We demonstrated a novel iterative method of dose calculation preformed in the Pinnacle plan to produce a combined dose distribution for external beam radiation and BT. We used it to evaluate the dose of target volume and normal tissues in the treatment of external beam radiation plus BT.
WOS关键词DEFORMABLE IMAGE REGISTRATION ; CANCER BRACHYTHERAPY ; UTERINE CERVIX ; THERAPY ; RADIOTHERAPY ; ACCUMULATION ; CARCINOMA
资助项目Medical Science Foundation of Zhejiang Health Bureau[2013KYB033] ; Medical Science Foundation of Zhejiang Health Bureau[2009B026] ; Medical Science Foundation of Zhejiang Health Bureau[2006A016] ; Medical Science Foundation of Zhejiang Health Bureau[2005B012] ; Medical Science Foundation of Zhejiang Health Bureau[2004B014] ; National Natural Science Foundation of China[81502646] ; National Natural Science Foundation of China[81502647]
WOS研究方向General & Internal Medicine
语种英语
WOS记录号WOS:000557513600015
出版者LIPPINCOTT WILLIAMS & WILKINS
资助机构Medical Science Foundation of Zhejiang Health Bureau ; National Natural Science Foundation of China
源URL[http://ir.hfcas.ac.cn:8080/handle/334002/45091]  
专题中国科学院合肥物质科学研究院
通讯作者Wang, Fangzheng; Jiang, Yangming
作者单位1.Chinese Acad Sci, Inst Canc & Basic Med ICBM, Hangzhou, Zhejiang, Peoples R China
2.Univ Chinese Acad Sci, Dept Radiat Oncol, Canc Hosp, Hangzhou, Zhejiang, Peoples R China
3.Zhejiang Canc Hosp, Dept Radiat Oncol, Hangzhou, Zhejiang, Peoples R China
4.Zhejiang Canc Hosp, Key Lab Radiat Oncol Zhejiang Prov, Hangzhou, Zhejiang, Peoples R China
5.Zhejiang Canc Hosp, Key Lab Head & Neck Canc Translat Res Zhejiang Pr, Hangzhou, Zhejiang, Peoples R China
6.Zhejiang Canc Hosp, Dept Breast Surg, Hangzhou, Zhejiang, Peoples R China
7.Zhejiang Canc Hosp, Dept Ultrasonog, Hangzhou, Zhejiang, Peoples R China
8.Zhejiang Canc Hosp, Dept Patho, Hangzhou, Zhejiang, Peoples R China
9.Chinese Acad Sci, Inst Remote Sensing & Digital Earth, Dept Digital Earth, Beijing 100101, Peoples R China
推荐引用方式
GB/T 7714		 Wang, Fangzheng,Jiang, Chuner,Liu, Tongxin,et al. Methodology of dose calculation for external beam radiation combined with high dose rate brachytherapy in the era of 3-dimensional treatment planning system[J]. MEDICINE,2020,99.
APA Wang, Fangzheng.,Jiang, Chuner.,Liu, Tongxin.,Sun, Quanquan.,Ye, Zhimin.,...&Jiang, Yangming.(2020).Methodology of dose calculation for external beam radiation combined with high dose rate brachytherapy in the era of 3-dimensional treatment planning system.MEDICINE,99.
MLA Wang, Fangzheng,et al."Methodology of dose calculation for external beam radiation combined with high dose rate brachytherapy in the era of 3-dimensional treatment planning system".MEDICINE 99(2020).

入库方式： OAI收割

来源：合肥物质科学研究院

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