Functional terpyridyl iron complexes forin vivophotoacoustic imaging
文献类型：期刊论文
| 作者 | Xiang, Pan1,2; Shen, Yu3; Shen, Jie3 ; Feng, Zhihui3; Sun, Min1; Zhang, Qiong3; Li, Shengli3; Li, Dandan3; Zhang, Guilong5; Wu, Zhengyan5
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| 刊名 | INORGANIC CHEMISTRY FRONTIERS
 |
| 出版日期 | 2020-07-28 |
| 卷号 | 7 |
| ISSN号 | 2052-1553 |
| DOI | 10.1039/d0qi00058b |
| 通讯作者 | Sun, Min(sunmin@ahu.edu.cn) ; Tian, Xiaohe(xiaohe.t@ahu.edu.cn) |
| 英文摘要 | Photoacoustic (PA) imaging has received extensive attention in the recent decade due to its ultra-high resolution in deep tissue penetration, whereas functional PA probes with tunable molecular structure at a low cost level remain a significant challenge. Herein, we have rationally designed three triple-pyridyl iron complexes with different water solubilities. These complexes show a higher photothermal conversion efficiency due to their rapid excited-state deactivation, making them suitable as PA probes. Notably, the photothermal conversion efficiency of one complex namedS-Fecould reach as high as 29.6%. In addition,S-Fehas excellent solubility and biocompatibility, which enable PA imagingin vivo. Significantly, further pharmacokinetics evaluation demonstrated that this complex showed minimal invasiveness for live animals and displayed a relatively fast metabolism rate. This study using inexpensive iron complexes as PA agents upgraded the toolbox for PA imaging and correlated multi-modal imaging applications. |
| WOS关键词 | BIOCOMPATIBILITY |
| 资助项目 | National Nature Science Foundation of China[21602003] ; National Nature Science Foundation of China[21871003] ; National Nature Science Foundation of China[51432001] ; National Nature Science Foundation of China[21701160] |
| WOS研究方向 | Chemistry |
| 语种 | 英语 |
| WOS记录号 | WOS:000553934700002 |
| 出版者 | ROYAL SOC CHEMISTRY |
| 资助机构 | National Nature Science Foundation of China |
| 源URL | [http://ir.hfcas.ac.cn:8080/handle/334002/70469]  |
| 专题 | 中国科学院合肥物质科学研究院 |
| 通讯作者 | Sun, Min; Tian, Xiaohe |
| 作者单位 | 1.Anhui Univ, Sch Life Sci, Hefei 230601, Peoples R China 2.Anhui Univ, Inst Phys Sci & Informat Technol, Hefei 230601, Peoples R China 3.Anhui Univ, Dept Chem, Anhui Prov Key Lab Chem Inorgan Organ Hybrid Func, Hefei 230601, Peoples R China 4.Chinese Acad Sci, CAS Ctr Excellence Nanosci, Inst Intelligent Machines, Hefei 230000, Peoples R China 5.Chinese Acad Sci, Hefei Inst Phys Sci, Key Lab High Magnet Field & Ion Beam Phys Biol, Hefei 230031, Peoples R China |
| 推荐引用方式 GB/T 7714 | Xiang, Pan,Shen, Yu,Shen, Jie,et al. Functional terpyridyl iron complexes forin vivophotoacoustic imaging[J]. INORGANIC CHEMISTRY FRONTIERS,2020,7. |
| APA | Xiang, Pan.,Shen, Yu.,Shen, Jie.,Feng, Zhihui.,Sun, Min.,...&Tian, Xiaohe.(2020).Functional terpyridyl iron complexes forin vivophotoacoustic imaging.INORGANIC CHEMISTRY FRONTIERS,7. |
| MLA | Xiang, Pan,et al."Functional terpyridyl iron complexes forin vivophotoacoustic imaging".INORGANIC CHEMISTRY FRONTIERS 7(2020). |
入库方式： OAI收割
来源：合肥物质科学研究院
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