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Automatic Planning for Nasopharyngeal Carcinoma Based on Progressive Optimization in RayStation Treatment Planning System

文献类型：期刊论文

作者Yang, Yiwei1,2,3; Shao, Kainan1,2,3; Zhang, Jie1,2,3; Chen, Ming1,4,5; Chen, Yuanyuan1,4,5; Shan, Guoping1,2,3
刊名TECHNOLOGY IN CANCER RESEARCH & TREATMENT
出版日期2020-06-18
卷号19
关键词VMAT automatic planning nasopharyngeal carcinoma RayStation script
ISSN号1533-0346
DOI10.1177/1533033820915710
通讯作者Yang, Yiwei(yangyw@zjcc.org.cn)
英文摘要Objective: To evaluate and quantify the planning performance of automatic planning (AP) with manual planning (MP) for nasopharyngeal carcinoma in the RayStation treatment planning system (TPS). Methods: A progressive and effective design method for AP of nasopharyngeal carcinoma was realized through automated scripts in this study. A total of 30 patients with nasopharyngeal carcinoma with initial treatment was enrolled. The target coverage, conformity index (CI), homogeneity index (HI), organs at risk sparing, and the efficiency of design and execution were compared between automatic and manual volumetric modulated arc therapy (VMAT) plans. Results: The results of the 2 design methods met the clinical dose requirement. The differences in D95 between the 2 groups in PTV1 and PTV2 showed statistical significance, and the MPs are higher than APs, but the difference in absolute dose was only 0.21% and 0.16%. The results showed that the conformity index of planning target volumes (PTV1, PTV2, PTVnd and PGTVnx+rpn [PGTVnx and PGTVrpn]), homogeneity index of PGTVnx+rpn, and HI of PTVnd in APs are better than that in MPs. For organs at risk, the APs are lower than the MPs, and the difference was statistically significant (P< .05). The manual operation time in APs was 83.21% less than that in MPs, and the computer processing time was 34.22% more. Conclusion: IronPython language designed by RayStation TPS has clinical application value in the design of automatic radiotherapy plan for nasopharyngeal carcinoma. The dose distribution of tumor target and organs at risk in the APs was similar or better than those in the MPs. The time of manual operation in the plan design showed a sharp reduction, thus significantly improving the work efficiency in clinical application.
WOS关键词MODULATED RADIATION-THERAPY ; MULTICRITERIA OPTIMIZATION ; NECK-CANCER ; LUNG-CANCER ; ARC THERAPY ; BEAM ANGLE ; AT-RISK ; IMRT ; HEAD ; QUALITY
资助项目National Key R&D Program of China[2017YFC0113201] ; Zhejiang Key RD Program[2019C03003] ; Zhejiang Medical and Health Project[2020KY472]
WOS研究方向Oncology
语种英语
WOS记录号WOS:000544664900001
出版者SAGE PUBLICATIONS INC
资助机构National Key R&D Program of China ; Zhejiang Key RD Program ; Zhejiang Medical and Health Project
源URL[http://ir.hfcas.ac.cn:8080/handle/334002/71147]  
专题中国科学院合肥物质科学研究院
通讯作者Yang, Yiwei
作者单位1.Chinese Acad Sci, Inst Canc & Basic Med ICBM, Hangzhou, Peoples R China
2.Univ Chinese Acad Sci, Canc Hosp, Dept Radiat Phys, Hangzhou, Peoples R China
3.Zhejiang Canc Hosp, Dept Radiat Phys, Hangzhou, Peoples R China
4.Univ Chinese Acad Sci, Canc Hosp, Dept Radiat Oncol, Hangzhou, Peoples R China
5.Zhejiang Canc Hosp, Dept Radiat Oncol, Hangzhou, Peoples R China
推荐引用方式
GB/T 7714		 Yang, Yiwei,Shao, Kainan,Zhang, Jie,et al. Automatic Planning for Nasopharyngeal Carcinoma Based on Progressive Optimization in RayStation Treatment Planning System[J]. TECHNOLOGY IN CANCER RESEARCH & TREATMENT,2020,19.
APA Yang, Yiwei,Shao, Kainan,Zhang, Jie,Chen, Ming,Chen, Yuanyuan,&Shan, Guoping.(2020).Automatic Planning for Nasopharyngeal Carcinoma Based on Progressive Optimization in RayStation Treatment Planning System.TECHNOLOGY IN CANCER RESEARCH & TREATMENT,19.
MLA Yang, Yiwei,et al."Automatic Planning for Nasopharyngeal Carcinoma Based on Progressive Optimization in RayStation Treatment Planning System".TECHNOLOGY IN CANCER RESEARCH & TREATMENT 19(2020).

入库方式： OAI收割

来源：合肥物质科学研究院

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