Chest CT of COVID-19 in patients with a negative first RT-PCR test Comparison with patients with a positive first RT-PCR test
文献类型：期刊论文
| 作者 | Chen, Zu-Hua3; Li, Yun-Jiang3; Wang, Xiu-Juan3 ; Ye, Yun-Feng3; Wu, Bao-Liang3; Zhang, Yan3; Xuan, Wei-Ling3; Bao, Jian-Feng1; Deng, Xue-Ying2,4
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| 刊名 | MEDICINE
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| 出版日期 | 2020-06-01 |
| 卷号 | 99 |
| ISSN号 | 0025-7974 |
| 关键词 | COVID-19 severe acute respiratory syndrome coronavirus 2 tomography x-ray computed |
| DOI | 10.1097/MD.0000000000020837 |
| 通讯作者 | Deng, Xue-Ying(a1145047838@163.com) |
| 英文摘要 | To compare clinical and imaging features between patients with an initial negative reverse-transcription-polymerase chain-reaction (RT-PCR) test and patients with an initial positive RT-PCR test. CT follow-up analysis in the negative RT-PCR group is also described. Thirty-three patients with SARS-CoV-2 infection confirmed by RT-PCR, with 216 lesions upon CT, were included. Demographic information and chest CT imaging features were collected. The average age in the whole study group was 46.9 +/- 11.1 years, with 18 males and 15 females. Patients in the positive RT-PCR test group were more likely to have a fever than patients in the negative RT-PCR test group (85.7% vs 50%,P < .05). Lesions in the positive group were more likely to be located in the peripheral area than lesions in the negative group (83.6% vs 68.2%,P < .05). Regarding the appearance of 216 lesions, ground-glass opacities (GGOs) with consolidation (43.2%) was the most common appearance in the negative group, followed by pure GGOs (31.8%), while in the positive group, pure GGOs (32%) and GGOs with interlobular septal thickening (32.8%) were both most frequent, and the difference between them was evident (P < .05). For the follow-up analysis, the largest short-axis of a lesion was smaller upon follow-up (median size 13.6 mm vs 14 mm), albeit by a smaller margin. Pure GGOs decreased in frequency, from 31.3% to 21.3%, while consolidation increased in frequency, from 7.5% to 12.5%. The manifestations of COVID-19 in patients with a first negative RT-PCR test and patients with a positive first RT-PCR test are different to some extent. The consolidation component may increase after follow-up. |
| WOS关键词 | CHINA |
| WOS研究方向 | General & Internal Medicine |
| 语种 | 英语 |
| 出版者 | LIPPINCOTT WILLIAMS & WILKINS |
| WOS记录号 | WOS:000549890000050 |
| 源URL | [http://ir.hfcas.ac.cn:8080/handle/334002/102963]  |
| 专题 | 中国科学院合肥物质科学研究院 |
| 通讯作者 | Deng, Xue-Ying |
| 作者单位 | 1.Zhejiang Chinese Med Univ, Hangzhou Xixi Hosp, Dept Sci & Educ, Hangzhou, Peoples R China 2.Univ Chinese Acad Sci, Zhejiang Canc Hosp, Canc Hosp, Dept Radiol, Banshandong Rd 1, Hangzhou, Peoples R China 3.Zhejiang Chinese Med Univ, Hangzhou Xixi Hosp, Dept Radiol, Hangzhou, Peoples R China 4.Chinese Acad Sci, Inst Canc & Basic Med ICBM, Hangzhou, Peoples R China |
| 推荐引用方式 GB/T 7714 | Chen, Zu-Hua,Li, Yun-Jiang,Wang, Xiu-Juan,et al. Chest CT of COVID-19 in patients with a negative first RT-PCR test Comparison with patients with a positive first RT-PCR test[J]. MEDICINE,2020,99. |
| APA | Chen, Zu-Hua.,Li, Yun-Jiang.,Wang, Xiu-Juan.,Ye, Yun-Feng.,Wu, Bao-Liang.,...&Deng, Xue-Ying.(2020).Chest CT of COVID-19 in patients with a negative first RT-PCR test Comparison with patients with a positive first RT-PCR test.MEDICINE,99. |
| MLA | Chen, Zu-Hua,et al."Chest CT of COVID-19 in patients with a negative first RT-PCR test Comparison with patients with a positive first RT-PCR test".MEDICINE 99(2020). |
入库方式： OAI收割
来源：合肥物质科学研究院
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