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Laser ablation in liquids for the assembly of Se@Au chain-oligomers with long-term stability for photothermal inhibition of tumor cells

文献类型：期刊论文

作者Cai, Yunyu2,3; Zhang, Yajun1,4; Ji, Sihan2,3; Ye, Yixing2,3; Wu, Shouliang2,3; Liu, Jun2,3; Chen, Shaopeng4; Liang, Changhao1,2,3
刊名JOURNAL OF COLLOID AND INTERFACE SCIENCE
出版日期2020-04-15
卷号566
关键词Au nanoparticle Se nanoparticle Chain-oligomer Laser ablation Green synthesis Photothermal therapy Directional assembly Bipolar interaction Long-term stability High photothermal transduction efficiency
ISSN号0021-9797
DOI10.1016/j.jcis.2020.01.098
通讯作者Cai, Yunyu(yycai@issp.ac.cn) ; Chen, Shaopeng(spchen035@ipp.ac.cn) ; Liang, Changhao(chliang@issp.ac.cn)
英文摘要For the potential use of Au nanoparticles (NPs) in photothermal therapy, it is important and effective to achieve the uniaxial assembly of Au NPs to allow enhanced absorption in the near infrared (NIR) region. Herein, we first presented the construction of amorphous selenium encapsulated gold (Se@Au) chainoligomers by successive laser ablation of Au and Se targets in sodium chloride solution without other toxic precursors, stabilizers, or templating molecules. Se@Au chain-oligomers showed evidently enhanced NIR absorption and excellent photothermal transduction efficiency (i), which was higher than 47% at 808 nm. After being stored for I year, the Se@Au colloids still exhibited outstanding photothermal performance. The cytotoxicity assay demonstrated that there is negligible toxicity of Se@Au chain-oligomers in cells, but cell viability declined to only 1% in phototherapeutic experiments that were implemented in vitro. In intracellular Reactive Oxygen Species (ROS) generation measurements, Se@Au chain-oligomers could trigger a 35.9% increment of ROS upon laser irradiation. The possible synergetic effects between the anticancer function of Se and photothermal behaviors of Se@Au intended to increase ROS level in cells. Therefore, such designed Se@Au chain-oligomers of high stability exhibit promising potential for their use as in vivo photothermal therapeutic agents. (C) 2020 Elsevier Inc. All rights reserved.
WOS关键词SELENIUM NANOPARTICLES ; OPTICAL-PROPERTIES ; GOLD NANORODS ; ABSORPTION ; TRANSITION ; APOPTOSIS ; SURFACES ; SPECTRA ; SOLVENT ; LIGHT
资助项目Instrument Developing Project of the Chinese Academy of Sciences[YZ201627] ; National Natural Science Foundation of China (NSFC)[51571186] ; National Natural Science Foundation of China (NSFC)[11674321] ; National Natural Science Foundation of China (NSFC)[51801205]
WOS研究方向Chemistry
语种英语
WOS记录号WOS:000521653900029
出版者ACADEMIC PRESS INC ELSEVIER SCIENCE
资助机构Instrument Developing Project of the Chinese Academy of Sciences ; National Natural Science Foundation of China (NSFC)
源URL[http://ir.hfcas.ac.cn:8080/handle/334002/103573]  
专题中国科学院合肥物质科学研究院
通讯作者Cai, Yunyu; Chen, Shaopeng; Liang, Changhao
作者单位1.Univ Sci & Technol China, Dept Mat Sci & Engn, Hefei 230026, Peoples R China
2.Chinese Acad Sci, Hefei Inst Phys Sci, Inst Solid State Phys, Key Lab Mat Phys, Hefei 230031, Anhui, Peoples R China
3.Chinese Acad Sci, Hefei Inst Phys Sci, Inst Solid State Phys, Anhui Key Lab Nanomat & Nanotechnol, Hefei 230031, Anhui, Peoples R China
4.Chinese Acad Sci, Hefei Inst Phys Sci, Key Lab High Magnet Field & Ion Beam Phys Biol, Hefei 230031, Anhui, Peoples R China
推荐引用方式
GB/T 7714		 Cai, Yunyu,Zhang, Yajun,Ji, Sihan,et al. Laser ablation in liquids for the assembly of Se@Au chain-oligomers with long-term stability for photothermal inhibition of tumor cells[J]. JOURNAL OF COLLOID AND INTERFACE SCIENCE,2020,566.
APA Cai, Yunyu.,Zhang, Yajun.,Ji, Sihan.,Ye, Yixing.,Wu, Shouliang.,...&Liang, Changhao.(2020).Laser ablation in liquids for the assembly of Se@Au chain-oligomers with long-term stability for photothermal inhibition of tumor cells.JOURNAL OF COLLOID AND INTERFACE SCIENCE,566.
MLA Cai, Yunyu,et al."Laser ablation in liquids for the assembly of Se@Au chain-oligomers with long-term stability for photothermal inhibition of tumor cells".JOURNAL OF COLLOID AND INTERFACE SCIENCE 566(2020).

入库方式： OAI收割

来源：合肥物质科学研究院

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