UV-induced over time transformation of AgNPs in commercial wound dressings and adverse biological effects on Caenorhabditis elegans
文献类型：期刊论文
| 作者 | Nie, Yaguang1,2; Wang, Jingjing2,3 ; Dai, Hui2; Wang, Juan2; Wang, Mudi2; Cheng, Lei2,3; Yang, Zhen2; Chen, Shaopeng2; Zhao, Guoping2; Wu, Lijun1,2
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| 刊名 | NANOIMPACT
 |
| 出版日期 | 2020 |
| 卷号 | 17 |
| 关键词 | released AgNPs Physicochemical transformation UV radiation toxicity Caenorhabditis elegans |
| ISSN号 | 2452-0748 |
| DOI | 10.1016/j.impact.2019.100193 |
| 通讯作者 | Xu, An(anxu@ipp.ac.cn) |
| 英文摘要 | Silver nanoparticles (AgNPs) are frequently used in commercial products; however, the knowledge on their release, environmental modification, and subsequent toxicity is still limited. In this study, we explored the leaking of AgNPs from an enhanced wound dressing under UV radiation as sterilization after use, and the toxic effects were determined using Caenorhabditis elegans (C. elegans). UV radiation was found to cause a series of over time physicochemical changes on the released AgNPs during the exposure: initially the formation of smaller secondary AgNPs (intermediate product), then the merging of Ag particles into structures beyond nanoscale (end product). Tissue-specific distribution and total accumulation of Ag in C. elegans both indicated that full UV treatment enhanced the uptake of AgNPs in the nematodes, which also inclined to release more Ag+. However, the end-product of UV treatment alleviated the neural and reproductive toxicity in C. elegans compared to unexposed particles, while the intermediate product induced more apoptosis in the gonad of the worms. Our data elucidated that UV-induced complex physicochemical changes on the released AgNPs were a crucial factor influencing its toxicity, and suggestions were given accordingly in order to reduce possible environmental threats from used wound dressings. The investigation on nano-silver wound dressings revealed that special attentions were needed for key environmental factors in both risk assessment and overall regulation of engineered nanomaterial enhanced products. |
| WOS关键词 | SILVER NANOPARTICLES ; CONSUMER PRODUCTS ; ENGINEERED NANOMATERIALS ; REPRODUCTIVE TOXICITY ; OXIDATIVE STRESS ; LIFE-CYCLE ; RELEASE ; LIGHT ; EXPOSURE ; BEHAVIOR |
| 资助项目 | National Natural Science Foundation of China[21507136] ; National Natural Science Foundation of China[21677147] ; National Natural Science Foundation of China[21607157] |
| WOS研究方向 | Environmental Sciences & Ecology ; Science & Technology - Other Topics |
| 语种 | 英语 |
| WOS记录号 | WOS:000519564300021 |
| 出版者 | ELSEVIER |
| 资助机构 | National Natural Science Foundation of China |
| 源URL | [http://ir.hfcas.ac.cn:8080/handle/334002/103759]  |
| 专题 | 中国科学院合肥物质科学研究院 |
| 通讯作者 | Xu, An |
| 作者单位 | 1.Anhui Univ, Inst Phys Sci & Informat Technol, Hefei 230601, Anhui, Peoples R China 2.Chinese Acad Sci, Hefei Inst Phys Sci, Key Lab High Magnet Field & Ion Beam Phys Biol, Anhui Prov Key Lab Environm Toxicol & Pollut Cont, Hefei 230031, Anhui, Peoples R China 3.Univ Sci & Technol China, Sch Environm Sci & Optoelect Technol, Hefei 230026, Anhui, Peoples R China |
| 推荐引用方式 GB/T 7714 | Nie, Yaguang,Wang, Jingjing,Dai, Hui,et al. UV-induced over time transformation of AgNPs in commercial wound dressings and adverse biological effects on Caenorhabditis elegans[J]. NANOIMPACT,2020,17. |
| APA | Nie, Yaguang.,Wang, Jingjing.,Dai, Hui.,Wang, Juan.,Wang, Mudi.,...&Xu, An.(2020).UV-induced over time transformation of AgNPs in commercial wound dressings and adverse biological effects on Caenorhabditis elegans.NANOIMPACT,17. |
| MLA | Nie, Yaguang,et al."UV-induced over time transformation of AgNPs in commercial wound dressings and adverse biological effects on Caenorhabditis elegans".NANOIMPACT 17(2020). |
入库方式： OAI收割
来源：合肥物质科学研究院
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