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Primary pulmonary lymphoepithelioma-like carcinoma

文献类型：期刊论文

作者Fan, Ying1,2,3,4; Li, Chenghui2,3,4; Qin, Jing2,3,4; Lu, Hongyang2,3,4
刊名MEDICAL ONCOLOGY
出版日期2020-03-07
卷号37
关键词PPLELC Clinical features Molecular characteristics Treatment PD-L1 Prognosis
ISSN号1357-0560
DOI10.1007/s12032-020-1344-3
通讯作者Lu, Hongyang(luhy@zjcc.org.cn)
英文摘要Primary pulmonary lymphoepithelioma-like carcinoma (PPLELC) is an extremely rare subtype of non-small-cell lung cancer (NSCLC) but differs from other NSCLC types. Most patients with PPLELC have almost no obvious clinical manifestations, and are often diagnosed in the advanced stage. Complete resection is the standard treatment for cases with early stage disease, while chemotherapy and radiotherapy are effective to some extent in late stage disease. High expression of PD-L1 in PPLELC tumor cells confers immunotherapy an important role in the treatment of PPLELC, and programmed death-1 (PD-1) inhibitors such as nivolumab and pembrolizumab may be optimal options for PPLELC patients. This review focuses on the clinical and pathologic features, treatment, and prognosis of PPLELC.
WOS关键词EPSTEIN-BARR-VIRUS ; COMPUTED-TOMOGRAPHY CHARACTERISTICS ; CELL LUNG-CARCINOMA ; MULTIMODALITY TREATMENT ; NIVOLUMAB ; ASSOCIATION ; FEATURES ; OUTCOMES ; PD-L1
资助项目Zhejiang Province Medical Science and Technology Project[2020ZH001]
WOS研究方向Oncology
语种英语
WOS记录号WOS:000519062400001
出版者HUMANA PRESS INC
资助机构Zhejiang Province Medical Science and Technology Project
源URL[http://ir.hfcas.ac.cn:8080/handle/334002/103797]  
专题中国科学院合肥物质科学研究院
通讯作者Lu, Hongyang
作者单位1.Wenzhou Med Univ, Clin Coll 1, Wenzhou 325035, Peoples R China
2.Chinese Acad Sci, ICBM, Hangzhou 310022, Peoples R China
3.Univ Chinese Acad Sci, Dept Thorac Med Oncol, Canc Hosp, Hangzhou 310022, Peoples R China
4.Zhejiang Canc Hosp, Zhejiang Key Lab Diag & Treatment Technol Thorac, Hangzhou 310022, Peoples R China
推荐引用方式
GB/T 7714		 Fan, Ying,Li, Chenghui,Qin, Jing,et al. Primary pulmonary lymphoepithelioma-like carcinoma[J]. MEDICAL ONCOLOGY,2020,37.
APA Fan, Ying,Li, Chenghui,Qin, Jing,&Lu, Hongyang.(2020).Primary pulmonary lymphoepithelioma-like carcinoma.MEDICAL ONCOLOGY,37.
MLA Fan, Ying,et al."Primary pulmonary lymphoepithelioma-like carcinoma".MEDICAL ONCOLOGY 37(2020).

入库方式： OAI收割

来源：合肥物质科学研究院

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