Ratiometric fluorescent nanosensor for dosage-sensitive visual discrimination of glucose based on electron transfer mechanism
文献类型：期刊论文
| 作者 | Zhang, Na4,5 ; Shen, Yujun4,5; Pang, Gaozong4,5; Chu, Suyun3; Han, Wei2; Mei, Qiong4,5; Hu, Xinlong4; Dong, Fengqi4; Shen, Yuxian4,5; Zhao, Tingting1,4,5
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| 刊名 | MICROCHEMICAL JOURNAL
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| 出版日期 | 2020-11-01 |
| 卷号 | 158 |
| 关键词 | Ratiometric fluorescence probe FITC QD@SiO2 Glucose level detection Energy transfer |
| ISSN号 | 0026-265X |
| DOI | 10.1016/j.microc.2020.105188 |
| 通讯作者 | Shen, Yuxian(shenyx@ahmu.edu.cn) ; Zhao, Tingting(ttzhao@ahmu.edu.cn) |
| 英文摘要 | Owing to the great role of glucose in biological systems and food industry, it is significant to maintain the dynamic balance of organisms. Various methods widely reported are focused on the glucose detection with high sensitivity and low detection limit. However, the sensor with ultra-low concentration sensitivity is not suitable for the direct detection of high concentration of glucose in human serum and food samples. Additionally, the application of ratiometric fluorescence probe is usually limited by the narrow range of color changes and insensitivity color change of the target. Here, a novel dual-emission ratiometric fluorescence probe with green to red fluorescence intensity of 6:1 was first constructed by fluorescein isothiocyanate (FITC) with green fluorescence as signal unit and silica coated quantum dot (QD@SiO2) with red fluorescence as the stable internal standard. The glucose was oxidized to generate H2O2 by the catalysis of glucose oxidase, which can oxidize Fe2+ to form Fe3+ ion. The formation of Fe3+ ion will cause the quenching of FITC fluorescence, which can realize the continuous fluorescence color change from green to yellow to orange to red for the qualitative and quantitative detection of blood glucose and fruit juice. The proposed method is cheap, simple, intuitive and has a wide detection range for glucose detection, which is of significance in designing the dual-emission ratiometric fluorescence sensor with wide range of color change. |
| WOS关键词 | QUANTUM DOTS ; APPLE JUICE ; SILICA ; PROBE ; ADULTERATION ; NANORODS ; SYSTEM ; SENSOR |
| 资助项目 | National Natural Science Foundation of China[21703255] ; National Natural Science Foundation of China[81973336] ; Research Fund for the Doctoral Program of Anhui Medical University[XJ201808] |
| WOS研究方向 | Chemistry |
| 语种 | 英语 |
| WOS记录号 | WOS:000573290700009 |
| 出版者 | ELSEVIER |
| 资助机构 | National Natural Science Foundation of China ; Research Fund for the Doctoral Program of Anhui Medical University |
| 源URL | [http://ir.hfcas.ac.cn:8080/handle/334002/104365]  |
| 专题 | 中国科学院合肥物质科学研究院 |
| 通讯作者 | Shen, Yuxian; Zhao, Tingting |
| 作者单位 | 1.Anhui Med Univ, Res & Engn Ctr Biomed Mat, Hefei 230032, Anhui, Peoples R China 2.Anhui Med Univ, Affiliated Hosp 2, Dept Anesthesia & Perioperat Med, Hefei 230601, Anhui, Peoples R China 3.Chinese Acad Sci, CAS Ctr Excellence Nanosci, Inst Intelligent Machines, Hefei 230031, Anhui, Peoples R China 4.Anhui Med Univ, Sch Basic Med Sci, Hefei 230032, Anhui, Peoples R China 5.Anhui Med Univ, Biopharmaceut Res Inst, Hefei 230032, Anhui, Peoples R China |
| 推荐引用方式 GB/T 7714 | Zhang, Na,Shen, Yujun,Pang, Gaozong,et al. Ratiometric fluorescent nanosensor for dosage-sensitive visual discrimination of glucose based on electron transfer mechanism[J]. MICROCHEMICAL JOURNAL,2020,158. |
| APA | Zhang, Na.,Shen, Yujun.,Pang, Gaozong.,Chu, Suyun.,Han, Wei.,...&Zhao, Tingting.(2020).Ratiometric fluorescent nanosensor for dosage-sensitive visual discrimination of glucose based on electron transfer mechanism.MICROCHEMICAL JOURNAL,158. |
| MLA | Zhang, Na,et al."Ratiometric fluorescent nanosensor for dosage-sensitive visual discrimination of glucose based on electron transfer mechanism".MICROCHEMICAL JOURNAL 158(2020). |
入库方式： OAI收割
来源：合肥物质科学研究院
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