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A materials-science perspective on tackling COVID-19

文献类型：期刊论文

作者Tang, Zhongmin6,7; Kong, Na6,7; Zhang, Xingcai8; Liu, Yuan6,7; Hu, Ping9; Mou, Shan10; Liljestrom, Peter11; Shi, Jianlin9; Tan, Weihong10,12,13; Kim, Jong Seung1
刊名NATURE REVIEWS MATERIALS
出版日期2020-10-14
ISSN号2058-8437
DOI10.1038/s41578-020-00247-y
通讯作者Farokhzad, Omid C.(ofarokhzad@bwh.harvard.edu) ; Tao, Wei(wtao@bwh.harvard.edu)
英文摘要Materials science provides tools and technologies for the protection against viral infections, as well as for the understanding, diagnosis, treatment and prevention of viral diseases. This Review discusses present and future directions in antiviral materials-science research, with a focus on COVID-19. The ongoing SARS-CoV-2 pandemic highlights the importance of materials science in providing tools and technologies for antiviral research and treatment development. In this Review, we discuss previous efforts in materials science in developing imaging systems and microfluidic devices for the in-depth and real-time investigation of viral structures and transmission, as well as material platforms for the detection of viruses and the delivery of antiviral drugs and vaccines. We highlight the contribution of materials science to the manufacturing of personal protective equipment and to the design of simple, accurate and low-cost virus-detection devices. We then investigate future possibilities of materials science in antiviral research and treatment development, examining the role of materials in antiviral-drug design, including the importance of synthetic material platforms for organoids and organs-on-a-chip, in drug delivery and vaccination, and for the production of medical equipment. Materials-science-based technologies not only contribute to the ongoing SARS-CoV-2 research efforts but can also provide platforms and tools for the understanding, protection, detection and treatment of future viral diseases.
WOS关键词MESSENGER-RNA VACCINES ; ZIKA VIRUS-INFECTION ; LABELED RABIES-VIRUS ; GENE-EXPRESSION ; CYTOKINE STORM ; INFLUENZA ; DELIVERY ; DNA ; NANOPARTICLES ; TRANSMISSION
资助项目US METAvivor Early Career Investigator Award[2018A020560] ; Harvard Medical School/Brigham and Women's Hospital Department of Anaesthesiology Basic Scientist Grant[2420 BPA075] ; Center for Nanomedicine Research Fund[2019A014810] ; Khoury Innovation Award[2020A003219] ; American Heart Association (AHA) Collaborative Science Award[2018A004190]
WOS研究方向Science & Technology - Other Topics ; Materials Science
语种英语
WOS记录号WOS:000577270200002
出版者NATURE RESEARCH
资助机构US METAvivor Early Career Investigator Award ; Harvard Medical School/Brigham and Women's Hospital Department of Anaesthesiology Basic Scientist Grant ; Center for Nanomedicine Research Fund ; Khoury Innovation Award ; American Heart Association (AHA) Collaborative Science Award
源URL[http://ir.hfcas.ac.cn:8080/handle/334002/104500]  
专题中国科学院合肥物质科学研究院
通讯作者Farokhzad, Omid C.; Tao, Wei
作者单位1.Korea Univ, Dept Chem, Seoul, South Korea
2.MIT, Koch Inst Integrat Canc Res, 77 Massachusetts Ave, Cambridge, MA 02139 USA
3.MIT, Dept Chem Engn, Cambridge, MA 02139 USA
4.Columbia Univ, Irving Med Ctr, Dept Syst Biol, New York, NY USA
5.Columbia Univ, Dept Biomed Engn, New York, NY USA
6.Harvard Med Sch, Brigham & Womens Hosp, Ctr Nanomed, Boston, MA 02115 USA
7.Harvard Med Sch, Brigham & Womens Hosp, Dept Anesthesiol, Boston, MA 02115 USA
8.Harvard Univ, Sch Engn & Appl Sci, Cambridge, MA 02138 USA
9.Chinese Acad Sci, Shanghai Inst Ceram, State Key Lab High Performance Ceram & Superfine, Shanghai, Peoples R China
10.Shanghai Jiao Tong Univ, Sch Med, State Key Lab Oncogenes & Related Genes, Inst Mol Med IMM,Renji Hosp, Shanghai, Peoples R China
推荐引用方式
GB/T 7714		 Tang, Zhongmin,Kong, Na,Zhang, Xingcai,et al. A materials-science perspective on tackling COVID-19[J]. NATURE REVIEWS MATERIALS,2020.
APA Tang, Zhongmin.,Kong, Na.,Zhang, Xingcai.,Liu, Yuan.,Hu, Ping.,...&Tao, Wei.(2020).A materials-science perspective on tackling COVID-19.NATURE REVIEWS MATERIALS.
MLA Tang, Zhongmin,et al."A materials-science perspective on tackling COVID-19".NATURE REVIEWS MATERIALS (2020).

入库方式： OAI收割

来源：合肥物质科学研究院

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