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High-Gradient Magnetic Field for Magnetic Nanoparticles Drug Delivery System

文献类型：期刊论文

作者Li, Da1,2; Ren, Yong3
刊名IEEE TRANSACTIONS ON APPLIED SUPERCONDUCTIVITY
出版日期2018-09-01
卷号28期号:6页码:7
关键词Gradient magnetic field magnetically targeted drug delivery system (MTDDS) superconducting magnet
ISSN号1051-8223
DOI10.1109/TASC.2018.2836999
通讯作者Ren, Yong(renyong@mail.ustc.edu.cn)
英文摘要Magnetic nanoparticles (MNPs), which can be transported through the vascular system and concentrated at the specific position of the body under an externalmagnetic field, are attracting increasing attention in tumor treatment. The MNPs should work under a high-gradient magnetic field for generating the enough magnetic forces to overcome the hydrodynamic drag force acting on the nanoparticles from the blood flow. Previous study on magnet-guided drug delivery has focused mainly on the synthesis and surface engineering of MNPs. In this study, the REBa2 Cu3OX [RE = rare earth] (REBCO) magnet, which is composed of three sets of coils, was designed for providing the gradient magnetic field in three perpendicular directions. The magnet system is geometrically compact to allow the mice to lie down. The three gradient magnetic fields and uniform magnetic fields near the magnetic field center can be generated in X-, Y-, and Z-directions, respectively. This paper describes the design and electromagnetic analysis of the superconducting magnet. In addition, the advantages and limitations of our design and future development will be presented.
WOS关键词SILICA NANOPARTICLES ; CANCER
资助项目National Natural Science Foundation of China[51406215] ; Anhui Provincial Natural Science Foundation[1408085QE90]
WOS研究方向Engineering ; Physics
语种英语
WOS记录号WOS:000435202300001
出版者IEEE-INST ELECTRICAL ELECTRONICS ENGINEERS INC
资助机构National Natural Science Foundation of China ; National Natural Science Foundation of China ; National Natural Science Foundation of China ; National Natural Science Foundation of China ; National Natural Science Foundation of China ; National Natural Science Foundation of China ; National Natural Science Foundation of China ; National Natural Science Foundation of China ; National Natural Science Foundation of China ; National Natural Science Foundation of China ; National Natural Science Foundation of China ; National Natural Science Foundation of China ; National Natural Science Foundation of China ; National Natural Science Foundation of China ; National Natural Science Foundation of China ; National Natural Science Foundation of China ; National Natural Science Foundation of China ; National Natural Science Foundation of China ; National Natural Science Foundation of China ; National Natural Science Foundation of China ; National Natural Science Foundation of China ; National Natural Science Foundation of China ; 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源URL[http://ir.hfcas.ac.cn:8080/handle/334002/38141]  
专题合肥物质科学研究院_中科院等离子体物理研究所
通讯作者Ren, Yong
作者单位1.First Peoples Hosp Hefei, Dept Tradit Chinese Med, Hefei 230061, Anhui, Peoples R China
2.Anhui Med Univ, Dept Tradit Chinese Med, Affiliated Hosp 3, Hefei 230061, Anhui, Peoples R China
3.Chinese Acad Sci, Inst Plasma Phys, Hefei Inst Phys Sci, Hefei 230031, Anhui, Peoples R China
推荐引用方式
GB/T 7714		 Li, Da,Ren, Yong. High-Gradient Magnetic Field for Magnetic Nanoparticles Drug Delivery System[J]. IEEE TRANSACTIONS ON APPLIED SUPERCONDUCTIVITY,2018,28(6):7.
APA Li, Da,&Ren, Yong.(2018).High-Gradient Magnetic Field for Magnetic Nanoparticles Drug Delivery System.IEEE TRANSACTIONS ON APPLIED SUPERCONDUCTIVITY,28(6),7.
MLA Li, Da,et al."High-Gradient Magnetic Field for Magnetic Nanoparticles Drug Delivery System".IEEE TRANSACTIONS ON APPLIED SUPERCONDUCTIVITY 28.6(2018):7.

入库方式： OAI收割

来源：合肥物质科学研究院

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