Salviachinensines A-F, Antiproliferative Phenolic Derivatives from the Chinese Medicinal Plant Salvia chinensis
文献类型：期刊论文
| 作者 | Wang, Qi1,4; Hu, Zhenquan1; Li, Xixiang1 ; Wang, Aoli1; Wu, Hong1; Liu, Jing1; Cao, Shugeng2; Liu, Qingsong1,3
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| 刊名 | JOURNAL OF NATURAL PRODUCTS
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| 出版日期 | 2018-11-01 |
| 卷号 | 81期号:11页码:2531-2538 |
| ISSN号 | 0163-3864 |
| DOI | 10.1021/acs.jnatprod.8b00638 |
| 通讯作者 | Cao, Shugeng(scao@hawaii.edu) ; Liu, Qingsong(qsliu97@hmfl.ac.cn) |
| 英文摘要 | Six new phenolic acid derivatives, salviachi-nensines A-F (1-6), together with 14 known compounds (7-20) were isolated from the Chinese medicinal plant Salvia chinensis. The structures of salviachinensines A-F (1-6) were elucidated by NMR spectroscopy, bioinspired chemical synthesis, ECD analysis, and quantum chemical calculation methods. Compounds 2 and 3 are a pair of cis-trans isomers, and compounds 5 and 6 a pair of epimers. The solvent induced isomerization of compounds 5 and 6 and the hypothetical biogenetic pathway of compounds 1-6, as well as the antiproliferative property and the ability of 1 to induce apoptosis and arrest cell cycle progression of MOLM-13 cells, were also investigated. |
| WOS关键词 | ACID PHENETHYL ESTER ; ATNICOMPLEMENTARY CONSTITUENTS ; CHEMICAL-CONSTITUENTS ; DITERPENOIDS ; ANTIOXIDANT ; TERPENOIDS ; INHIBITORS ; ROOTS |
| 资助项目 | National Natural Science Foundation of China[U1432250] ; National Natural Science Foundation of China[U1532154] ; National Natural Science Foundation of China[81773777] ; National Natural Science Foundation of China[81473088] ; National Natural Science Foundation of China[81703559] ; China Postdoctoral Science Foundation[2017M622036] ; China Postdoctoral Science Foundation[2018M630720] ; China Postdoctoral Science Foundation[2018T110634] ; Natural Science Foundation of Anhui Province[1808085MH274] ; Frontier Science Key Research Program of CAS[QYZDB-SW-SLH037] |
| WOS研究方向 | Plant Sciences ; Pharmacology & Pharmacy |
| 语种 | 英语 |
| WOS记录号 | WOS:000451496100024 |
| 出版者 | AMER CHEMICAL SOC |
| 资助机构 | National Natural Science Foundation of China ; National Natural Science Foundation of China ; National Natural Science Foundation of China ; National Natural Science Foundation of China ; China Postdoctoral Science Foundation ; China Postdoctoral Science Foundation ; China Postdoctoral Science Foundation ; China Postdoctoral Science Foundation ; Natural Science Foundation of Anhui Province ; Natural Science Foundation of Anhui Province ; Natural Science Foundation of Anhui Province ; Natural Science Foundation of Anhui Province ; Frontier Science Key Research Program of CAS ; Frontier Science Key Research Program of CAS ; Frontier Science Key Research Program of CAS ; Frontier Science Key Research Program of CAS ; National Natural Science Foundation of China ; National Natural Science Foundation of China ; National Natural Science Foundation of China ; National Natural Science Foundation of China ; China Postdoctoral Science Foundation ; China Postdoctoral Science Foundation ; China Postdoctoral Science Foundation ; China Postdoctoral Science Foundation ; Natural Science Foundation of Anhui Province ; Natural Science Foundation of Anhui Province ; Natural Science Foundation of Anhui Province ; Natural Science Foundation of Anhui Province ; Frontier Science Key Research Program of CAS ; Frontier Science Key Research Program of CAS ; Frontier Science Key Research Program of CAS ; Frontier Science Key Research Program of CAS |
| 源URL | [http://ir.hfcas.ac.cn:8080/handle/334002/40238]  |
| 专题 | 合肥物质科学研究院_中科院强磁场科学中心 |
| 通讯作者 | Cao, Shugeng; Liu, Qingsong |
| 作者单位 | 1.Chinese Acad Sci, High Field Magnet Lab, Key Lab High Magnet Field & Ion Beam Phys Biol, Hefei Inst Phys Sci, Hefei 230031, Anhui, Peoples R China 2.Univ Hawaii, Dept Pharmaceut Sci, Daniel K Inouye Coll Pharm, Hilo, HI 96720 USA 3.Anhui Univ, Inst Phys Sci & Informat Technol, Hefei 230601, Anhui, Peoples R China 4.Qingdao Univ, Inst Chron Dis, Qingdao 266003, Peoples R China |
| 推荐引用方式 GB/T 7714 | Wang, Qi,Hu, Zhenquan,Li, Xixiang,et al. Salviachinensines A-F, Antiproliferative Phenolic Derivatives from the Chinese Medicinal Plant Salvia chinensis[J]. JOURNAL OF NATURAL PRODUCTS,2018,81(11):2531-2538. |
| APA | Wang, Qi.,Hu, Zhenquan.,Li, Xixiang.,Wang, Aoli.,Wu, Hong.,...&Liu, Qingsong.(2018).Salviachinensines A-F, Antiproliferative Phenolic Derivatives from the Chinese Medicinal Plant Salvia chinensis.JOURNAL OF NATURAL PRODUCTS,81(11),2531-2538. |
| MLA | Wang, Qi,et al."Salviachinensines A-F, Antiproliferative Phenolic Derivatives from the Chinese Medicinal Plant Salvia chinensis".JOURNAL OF NATURAL PRODUCTS 81.11(2018):2531-2538. |
入库方式： OAI收割
来源：合肥物质科学研究院
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