Kinetic study of lipase-catalyzed esterification of furoic acid to methyl-2-furoate
文献类型：期刊论文
| 作者 | Zhang, Yu2 ; Di, Xiaohui1,2; Wang, Wen2; Song, Miaojia1,2; Yu, Qiang2; Wang, Zhongming2; Yuan, Zhenhong2; Chen, Xiaoyan1,2; Xu, Huijuan2; Guo, Ying2
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| 刊名 | BIOCHEMICAL ENGINEERING JOURNAL
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| 出版日期 | 2020-09-15 |
| 卷号 | 161页码:8 |
| 关键词 | Enzymatic kinetics Heterogeneous Fitting Binary regression Reversible second-order reaction |
| ISSN号 | 1369-703X |
| DOI | 10.1016/j.bej.2020.107587 |
| 通讯作者 | Yu, Qiang(yuqiang@ms.giec.ac.cn) |
| 英文摘要 | Methyl-2-furoate (MF) is a high-value compound, and can be produced via esterification of furoic acid derived from biobased furfural. Herein, CAL-B and [bmim] [PF6] were the most efficient lipase and organic medium for MF production, respectively. Based on mass action law and reaction reversibility, a mathematical model was developed. Data analysis showed the newly proposed binary regression was apparently more suitable compared to the commonly used unitary regression. The enzymatic promotion factor m, for esterification and hydrolysis was 1.8159 and 0, while the alcohol inhibition factor n(i) was 0 and 0.06436, respectively. Both the activation energy E-a,E-i for esterification and hydrolysis was 84 kJ/mol, and the pre-exponential factor A(i) was 7.1408 x 10(13) and 7.8962 x 10(13), respectively. Kinetics study demonstrated that CAL-B held significantly more dominant esterification activity compared to hydrolysis activity, whereas alcohol just inhibited hydrolysis activity instead of esterification activity, and the relationship between esterification/hydrolysis rate constants k(i) and temperature agreed with Arrhenius equation. The maximum MF yield was 82.5 % at 24 h, and the yield decreased to 75.4 % after 1 re-use of CAL-B, but maintained about 20 % for next 4 cycles. Totally, the developed model and binary regression analysis method is ideal for in-depth examination of lipase-catalyzed kinetics in heterogeneous system. |
| WOS关键词 | OXIDATIVE ESTERIFICATION ; LEVULINIC ACID ; IONIC LIQUIDS ; IMMOBILIZATION ; STABILIZATION ; BIODIESEL ; ENZYMES |
| 资助项目 | National Natural Science Foundation of China[21978288] ; National Natural Science Foundation of China[51876206] ; National Key R&D Program of China[2018YFB1501701] ; National Key R&D Program of China[2019YFC1906602] ; Municipal Science and Technology Project of Guangzhou (China)[201804010081] |
| WOS研究方向 | Biotechnology & Applied Microbiology ; Engineering |
| 语种 | 英语 |
| WOS记录号 | WOS:000552131300002 |
| 出版者 | ELSEVIER |
| 资助机构 | National Natural Science Foundation of China ; National Key R&D Program of China ; Municipal Science and Technology Project of Guangzhou (China) |
| 源URL | [http://ir.giec.ac.cn/handle/344007/27517]  |
| 专题 | 中国科学院广州能源研究所 |
| 通讯作者 | Yu, Qiang |
| 作者单位 | 1.Univ Chinese Acad Sci, Beijing 100049, Peoples R China 2.Chinese Acad Sci, Guangzhou Inst Energy Convers, CAS Key Lab Renewable Energy, Guangdong Prov Key Lab New & Renewable Energy Res, Guangzhou 510640, Peoples R China |
| 推荐引用方式 GB/T 7714 | Zhang, Yu,Di, Xiaohui,Wang, Wen,et al. Kinetic study of lipase-catalyzed esterification of furoic acid to methyl-2-furoate[J]. BIOCHEMICAL ENGINEERING JOURNAL,2020,161:8. |
| APA | Zhang, Yu.,Di, Xiaohui.,Wang, Wen.,Song, Miaojia.,Yu, Qiang.,...&Guo, Ying.(2020).Kinetic study of lipase-catalyzed esterification of furoic acid to methyl-2-furoate.BIOCHEMICAL ENGINEERING JOURNAL,161,8. |
| MLA | Zhang, Yu,et al."Kinetic study of lipase-catalyzed esterification of furoic acid to methyl-2-furoate".BIOCHEMICAL ENGINEERING JOURNAL 161(2020):8. |
入库方式： OAI收割
来源：广州能源研究所
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