Ancient mitogenomes show plateau populations from last 5200 years partially contributed to present-day Tibetans
文献类型:期刊论文
作者 | Ding, Manyu1,13,14,15; Wang, Tianyi2,13; Ko, Albert Min-Shan13; Chen, Honghai2; Wang, Hui3,4; Dong, Guanghui5; Lu, Hongliang6; He, Wei7; Wangdue, Shargan7; Yuan, Haibing9,10 |
刊名 | PROCEEDINGS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES |
出版日期 | 2020-03-25 |
卷号 | 287期号:1923页码:6 |
ISSN号 | 0962-8452 |
关键词 | ancient DNA population genetics of humans Tibetan prehistory |
DOI | 10.1098/rspb.2019.2968 |
通讯作者 | Fu, Qiaomei(fuqiaomei@ivpp.ac.cn) |
英文摘要 | The clarification of the genetic origins of present-day Tibetans requires an understanding of their past relationships with the ancient populations of the Tibetan Plateau. Here we successfully sequenced 67 complete mitochondrial DNA genomes of 5200 to 300-year-old humans from the plateau. Apart from identifying two ancient plateau lineages (haplogroups D4j1b and M9a1a1c1b1a) that suggest some ancestors of Tibetans came from low-altitude areas 4750 to 2775 years ago and that some were involved in an expansion of people moving between high-altitude areas 2125 to 1100 years ago, we found limited evidence of recent matrilineal continuity on the plateau. Furthermore, deep learning of the ancient data incorporated into simulation models with an accuracy of 97% supports that present-day Tibetan matrilineal ancestry received partial contribution rather than complete continuity from the plateau populations of the last 5200 years. |
WOS关键词 | PERMANENT HUMAN OCCUPATION ; GENOME SEQUENCE ; GENETICS ; CAVE |
资助项目 | National Key R&D Program of China[2016YFE0203700] ; CAS[XDB26000000] ; NSFC[41925009] ; NSFC[91731303] ; NSFC[41672021] ; NSFC[41630102] ; Chinese Academy of Sciences[QYZDBSSWDQC003] ; Chinese Academy of Sciences[XDA19050102] ; Tencent Foundation through the XPLORER PRIZE ; Howard Hughes Medical Institute[55008731] ; Second Tibetan Plateau Scientific Expedition and Research Program (STEP)[2019QZKK0601] ; China Postdoctoral Science Foundation[2017M623018] ; Sichuan University Research Cluster for Regional History and Frontier Studies |
WOS研究方向 | Life Sciences & Biomedicine - Other Topics ; Environmental Sciences & Ecology ; Evolutionary Biology |
语种 | 英语 |
出版者 | ROYAL SOC |
WOS记录号 | WOS:000546950500011 |
资助机构 | National Key R&D Program of China ; CAS ; NSFC ; Chinese Academy of Sciences ; Tencent Foundation through the XPLORER PRIZE ; Howard Hughes Medical Institute ; Second Tibetan Plateau Scientific Expedition and Research Program (STEP) ; China Postdoctoral Science Foundation ; Sichuan University Research Cluster for Regional History and Frontier Studies |
源URL | [http://119.78.100.205/handle/311034/17943] |
专题 | 中国科学院古脊椎动物与古人类研究所 |
通讯作者 | Fu, Qiaomei |
作者单位 | 1.Chinese Acad Sci, Ctr Excellence Anim Evolut & Genet, Kunming 650223, Yunnan, Peoples R China 2.Northwest Univ, Sch Cultural Heritage, Xian 710069, Peoples R China 3.Fudan Univ, Fudan Archaeol Sci Inst, Shanghai 200433, Peoples R China 4.Gansu Prov Inst Cultural Relics & Archaeol, Lanzhou 730030, Peoples R China 5.Lanzhou Univ, Coll Earth & Environm Sci, Key Lab Western Chinas Environm Syst, Minist Educ, Lanzhou 730000, Peoples R China 6.Sichuan Univ, Dept Archaeol, Chengdu 610064, Peoples R China 7.Tibet Inst Conservat & Res Cultural Relics, Lhasa 850000, Peoples R China 8.Univ Richmond, Dept Biol, Richmond, VA 23173 USA 9.Sichuan Univ, Natl Demonstrat Ctr Expt Archaeol Educ, Chengdu 610064, Peoples R China 10.Sichuan Univ, Dept Archaeol, Chengdu 610064, Peoples R China |
推荐引用方式 GB/T 7714 | Ding, Manyu,Wang, Tianyi,Ko, Albert Min-Shan,et al. Ancient mitogenomes show plateau populations from last 5200 years partially contributed to present-day Tibetans[J]. PROCEEDINGS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES,2020,287(1923):6. |
APA | Ding, Manyu.,Wang, Tianyi.,Ko, Albert Min-Shan.,Chen, Honghai.,Wang, Hui.,...&Fu, Qiaomei.(2020).Ancient mitogenomes show plateau populations from last 5200 years partially contributed to present-day Tibetans.PROCEEDINGS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES,287(1923),6. |
MLA | Ding, Manyu,et al."Ancient mitogenomes show plateau populations from last 5200 years partially contributed to present-day Tibetans".PROCEEDINGS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES 287.1923(2020):6. |
入库方式: OAI收割
来源:古脊椎动物与古人类研究所
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