中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
Mass-transfer based modeling to investigate iodine staining effects for enhanced contrast X-ray computed tomography

文献类型:期刊论文

作者Li, Zhi-Heng2,3; Yan, Fei1; Ketcham, Richard A.4; Colbert, Matthew W.4; Clarke, Julia A.4
刊名PALAEOWORLD
出版日期2019-12-01
卷号28期号:4页码:562-571
关键词Computed tomography Iodine Contrast Staining Birds
ISSN号1871-174X
DOI10.1016/j.palwor.2018.10.004
通讯作者Li, Zhi-Heng(lizhiheng@ivpp.ac.cn)
英文摘要Iodine staining combined with X-ray computed tomography (CT) has become a core approach in anatomy, offering three-dimensional and essentially non-destructive imaging of soft tissues. Although there have been rapid advances in methodologies and techniques, the mechanisms underlying diffusible iodine contrast-enhanced CT are not yet fully understood. The protocols for staining samples of differing sizes and tissue types have not yet been justified theoretically. Here we utilize mass transfer modeling to simulate iodine diffusion and predict iodine concentrations within distinct tissue types. We also undertake iodine staining experiments to visualize the detailed anatomy and contrast effects on whole-body avian specimens using different concentrations of iodine solution to compare with model simulation results. The simulations effectively explain most observed concentration changes in differently-sized samples over distinct iodine treatment durations. These results also provide insight into the mechanisms behind the efficacy of solution replenishment for enhancing staining effects. Both consistencies and inconsistencies between our simulation and experimental results regarding iodine concentration in tissues will inform further investigations to optimize iodine staining protocols. (C) 2018 Elsevier Ireland Ltd Elsevier B.V. and Nanjing Institute of Geology and Palaeontology, CAS. Published by Elsevier B.V. All rights reserved.
WOS关键词MICROCT IMAGES ; DICECT ; TOOL ; CT
资助项目Strategic Priority Research Program of the Chinese Academy of Sciences[XDA19050102] ; Strategic Priority Research Program of the Chinese Academy of Sciences[XDA 20070203] ; Strategic Priority Research Program of the Chinese Academy of Sciences[XDB26000000] ; One Hundred Talent Program of the Chinese Academy of Sciences ; NSFC[41772013] ; Gordon and Betty Moore Foundation[4498] ; NSF[EAR1258878]
WOS研究方向Paleontology
语种英语
WOS记录号WOS:000499969100014
出版者ELSEVIER
资助机构Strategic Priority Research Program of the Chinese Academy of Sciences ; One Hundred Talent Program of the Chinese Academy of Sciences ; NSFC ; Gordon and Betty Moore Foundation ; NSF
源URL[http://119.78.100.205/handle/311034/16786]  
专题古脊椎动物与古人类研究所_图书馆1
通讯作者Li, Zhi-Heng
作者单位1.Rice Univ, Dept Civil & Environm Engn, Houston, TX USA
2.Chinese Acad Sci, Inst Vertebrate Paleontol & Paleoanthropol, Key Lab Vertebrate Evolut & Human Origins, Beijing 100044, Peoples R China
3.CAS Ctr Excellence Life & Paleoenvironm, Beijing 100044, Peoples R China
4.Univ Texas Austin, Dept Geol Sci, Austin, TX 78712 USA
推荐引用方式
GB/T 7714
Li, Zhi-Heng,Yan, Fei,Ketcham, Richard A.,et al. Mass-transfer based modeling to investigate iodine staining effects for enhanced contrast X-ray computed tomography[J]. PALAEOWORLD,2019,28(4):562-571.
APA Li, Zhi-Heng,Yan, Fei,Ketcham, Richard A.,Colbert, Matthew W.,&Clarke, Julia A..(2019).Mass-transfer based modeling to investigate iodine staining effects for enhanced contrast X-ray computed tomography.PALAEOWORLD,28(4),562-571.
MLA Li, Zhi-Heng,et al."Mass-transfer based modeling to investigate iodine staining effects for enhanced contrast X-ray computed tomography".PALAEOWORLD 28.4(2019):562-571.

入库方式: OAI收割

来源:古脊椎动物与古人类研究所

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