Octyl substituted butenolides from marine-derived Streptomyces koyangensis
文献类型：期刊论文
| 作者 | Huang, Hongbo; Song, Yongxiang; Zang, Ruochen; Wang, Xin; Ju, Jianhua; [Huang, Hongbo; Song, Yongxiang; Ju, Jianhua] Chinese Acad Sci, CAS Key Lab Trop Marine Bioresources & Ecol, Guangdong Key Lab Marine Mat Med, RNAM Ctr Marine Microbiol,South China Sea Inst Oc, Guangzhou, Guangdong, Peoples R China; [Huang, Hongbo; Song, Yongxiang |
| 刊名 | NATURAL PRODUCT RESEARCH
 |
| 关键词 | Butenolide (4S)-10-hydroxy-10-methyl-11-oxo-dodec-2-en-1 4-olide Streptomyces koyangensis marine actinomycete antiviral activity |
| DOI | 10.1080/14786419.2019.1686368 |
| 英文摘要 | A new butenolide derivative (1) featuring octyl substitution at gamma-position, together with four known analogues (2-5) were isolated from marine-derived Streptomyces koyangensis SCSIO 5802. The structure of 1 was elucidated by HR-MS and NMR spectroscopic data analyses. The absolute configuration of the stereo centre in lactone ring of 1 was determined by comparison of CD spectrum with those of known compounds. Compound 1 exhibited mild antiviral activity against herpes simplex virus with EC50 value of 25.4 mu M. |
| 资助机构 | National Natural Science Foundation of ChinaNational Natural Science Foundation of China (NSFC) [41476133, 41676151, 81425022] ; National Natural Science Foundation of ChinaNational Natural Science Foundation of China (NSFC) [41476133, 41676151, 81425022] |
| 源URL | [http://ir.scsio.ac.cn/handle/344004/18235]  |
| 专题 | 南海海洋研究所_中科院海洋生物资源可持续利用重点实验室 |
| 推荐引用方式 GB/T 7714 | Huang, Hongbo,Song, Yongxiang,Zang, Ruochen,et al. Octyl substituted butenolides from marine-derived Streptomyces koyangensis[J]. NATURAL PRODUCT RESEARCH. |
| APA | Huang, Hongbo.,Song, Yongxiang.,Zang, Ruochen.,Wang, Xin.,Ju, Jianhua.,...&Wang, Xin] Qingdao Natl Lab Marine Sci & Technol, Innovat Marine Drug Screening & Evaluat Ctr, Qingdao, Shandong, Peoples R China. |
| MLA | Huang, Hongbo,et al."Octyl substituted butenolides from marine-derived Streptomyces koyangensis".NATURAL PRODUCT RESEARCH |
入库方式： OAI收割
来源：南海海洋研究所
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