Diisonitrile-Mediated Reactive Oxygen Species Accumulation Leads to Bacterial Growth Inhibition
文献类型：期刊论文
| 作者 | Zhu, Mengyi; Wang, Lijuan2; Zhang, Wei; Liu, Zhiwen2; Ali, Muhammad3; Imtiaz, Muhammad1; He, Jing |
| 刊名 | JOURNAL OF NATURAL PRODUCTS
 |
| 出版日期 | 2020 |
| 卷号 | 83期号:5页码:1634 |
| ISSN号 | 0163-3864 |
| DOI | 10.1021/acs.jnatprod.0c00125 |
| 英文摘要 | The diisonitrile copper chelator SF2768 biosynthesized by Streptomyces thioluteus functions as a chalkophore that transports extracellular copper into producer cells in a complexed form. It was demonstrated that the treatment of eight bacteria, including Bacillus subtilis and Acinetobacter baumannii, with SF2768 led to a moderate growth inhibition which is associated with an increased level of reactive oxygen species (ROS). In addition, SF2768 and its diisonitrile analogues proved to be effective tyrosinase inhibitors. Three new analogues, SF2768 I, K, and L, were identified by detailed spectroscopic analysis. |
| 资助机构 | National Natural Science Foundation of ChinaNational Natural Science Foundation of China (NSFC) [31870089]; Natural Science Foundation for Distinguished Young Scholars of Hubei Province of China [2018CFA069]; Fundamental Research Funds for the Central UniversitiesFundamental Research Funds for the Central Universities [2662018PY053] ; National Natural Science Foundation of ChinaNational Natural Science Foundation of China (NSFC) [31870089]; Natural Science Foundation for Distinguished Young Scholars of Hubei Province of China [2018CFA069]; Fundamental Research Funds for the Central UniversitiesFundamental Research Funds for the Central Universities [2662018PY053] |
| 源URL | [http://ir.scsio.ac.cn/handle/344004/18421]  |
| 专题 | 南海海洋研究所_中科院海洋生物资源可持续利用重点实验室 |
| 作者单位 | 1.COMSATS Univ Islamabad, Dept Biotechnol, Abbottabad 22060, Pakistan 2.Huazhong Agr Univ, Coll Life Sci & Technol, State Key Lab Agr Microbiol, Wuhan 430070, Peoples R China 3.Chinese Acad Sci, South China Sea Inst Oceanol, Guangdong Key Lab Marine Mat Med, CAS Key Lab Trop Marine Bioresources & Ecol,RNAM, Guangzhou 510301, Peoples R China 4.Natl Inst Biotechnol & Genet Engn, Soil & Environm Biotechnol Div, Faisalabad 38000, Pakistan |
| 推荐引用方式 GB/T 7714 | Zhu, Mengyi,Wang, Lijuan,Zhang, Wei,et al. Diisonitrile-Mediated Reactive Oxygen Species Accumulation Leads to Bacterial Growth Inhibition[J]. JOURNAL OF NATURAL PRODUCTS,2020,83(5):1634, 1640. |
| APA | Zhu, Mengyi.,Wang, Lijuan.,Zhang, Wei.,Liu, Zhiwen.,Ali, Muhammad.,...&He, Jing.(2020).Diisonitrile-Mediated Reactive Oxygen Species Accumulation Leads to Bacterial Growth Inhibition.JOURNAL OF NATURAL PRODUCTS,83(5),1634. |
| MLA | Zhu, Mengyi,et al."Diisonitrile-Mediated Reactive Oxygen Species Accumulation Leads to Bacterial Growth Inhibition".JOURNAL OF NATURAL PRODUCTS 83.5(2020):1634. |
入库方式： OAI收割
来源：南海海洋研究所
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