Two new aromatic polyketides from a deep-sea fungus Penicillium sp. SCSIO 06720
文献类型:期刊论文
作者 | Guo, Cui; Lin, Xiu-Ping; Liao, Sheng-Rong; Yang, Bin; Zhou, Xue-Feng; Yang, Xian-Wen; Tian, Xin-Peng; Wang, Jun-Feng; Liu, Yong-Hong |
刊名 | NATURAL PRODUCT RESEARCH
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出版日期 | 2020 |
卷号 | 34期号:9页码:1197 |
关键词 | Deep-sea fungus Penicillium sp phenyl derivative benzopyranone |
ISSN号 | 1478-6419 |
DOI | 10.1080/14786419.2018.1553880 |
英文摘要 | Two new compounds, 5-[2-hydroxypropane-1-yl]-2,6-dimethlbenzene-1,3-diol (1) and coniochaetone L (2), together with 19 known compounds (3-21), were isolated from a deep-sea fungus, Penicillium sp. SCSIO 06720. Their structures and absolute configurations were elucidated by detailed NMR, MS spectroscopic analyses, chiral-phase HPLC analysis, and electronic circular dichroism spectra. All the isolated compounds (1-21) were tested for their antibacterial and HIV latency-reversal activities. Among these compounds, compound 16 showed moderate antibacterial activities against Staphylococcus aureus ATCC 29213 and Methicillin-Resistant Staphylococcus Aureus-shh-1 with MIC values of 10.4 +/- 3.7 mu g/mL and 46.9 +/- 29.7 mu g/mL, respectively, which were comparable to that of the positive control ampicillin with MIC values of 0.5 +/- 0.4 mu g/mL and 2.7 +/- 0.9 mu g/mL, respectively. |
资助机构 | National Natural Science Foundation of ChinaNational Natural Science Foundation of China (NSFC) [21772210, 41476135, 41676130, 41776169, 81741154, 81741158]; Science and Technology Project of Guangdong Province [2016A020222010]; Strategic Priority Research Program of the Chinese Academy of SciencesChinese Academy of Sciences [XDA11030403] ; National Natural Science Foundation of ChinaNational Natural Science Foundation of China (NSFC) [21772210, 41476135, 41676130, 41776169, 81741154, 81741158]; Science and Technology Project of Guangdong Province [2016A020222010]; Strategic Priority Research Program of the Chinese Academy of SciencesChinese Academy of Sciences [XDA11030403] |
源URL | [http://ir.scsio.ac.cn/handle/344004/18431] ![]() |
专题 | 南海海洋研究所_中科院海洋生物资源可持续利用重点实验室 |
作者单位 | 1.Lin, Xiu-Ping 2.[Guo, Cui 3.[Guo, Cui 4.Zhou, Xue-Feng 5.Tian, Xin-Peng 6.Wang, Jun-Feng 7.Univ Chinese Acad Sci, Beijing, Peoples R China 8.Chinese Acad Sci, South China Sea Inst Oceanol, CAS Key Lab Trop Marine Bioresources & Ecol, Guangdong Key Lab Marine Mat Med,RNAM Ctr Marine, Guangzhou, Peoples R China 9.State Ocean Adm, Inst Oceanog 3, State Key Lab Breeding Base Marine Genet Resourc, Key Lab Marine Genet Resources, Xiamen, Peoples R China 10.Liao, Sheng-Rong |
推荐引用方式 GB/T 7714 | Guo, Cui,Lin, Xiu-Ping,Liao, Sheng-Rong,et al. Two new aromatic polyketides from a deep-sea fungus Penicillium sp. SCSIO 06720[J]. NATURAL PRODUCT RESEARCH,2020,34(9):1197, 1205. |
APA | Guo, Cui.,Lin, Xiu-Ping.,Liao, Sheng-Rong.,Yang, Bin.,Zhou, Xue-Feng.,...&Liu, Yong-Hong.(2020).Two new aromatic polyketides from a deep-sea fungus Penicillium sp. SCSIO 06720.NATURAL PRODUCT RESEARCH,34(9),1197. |
MLA | Guo, Cui,et al."Two new aromatic polyketides from a deep-sea fungus Penicillium sp. SCSIO 06720".NATURAL PRODUCT RESEARCH 34.9(2020):1197. |
入库方式: OAI收割
来源:南海海洋研究所
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