Developmental toxicity of copper in marine medaka (Oryzias melastigma) embryos and larvae
文献类型：期刊论文
| 作者 | Wang, Rui-Fang; Zhu, Li-Mei; Zhang, Jun; An, Xiao-Ping; Yang, Yan-Ping; Song, Min; Zhang, Li1,3,4 |
| 刊名 | CHEMOSPHERE
 |
| 出版日期 | 2020 |
| 卷号 | 247页码:125923 |
| 关键词 | Marine fish Medaka Copper Embryo Development Bioaccumulation |
| ISSN号 | 0045-6535 |
| DOI | 10.1016/j.chemosphere.2020.125923 |
| 英文摘要 | Copper as developmental toxicants have been reported extensively in freshwater fish, however, the sublethal and chronic toxic effects of Cu to the early life stages of marine fish are not clear. Embryo (3-5 hpf) and newly hatched larvae of marine medaka (Oryzias melastigma) were exposed to 0.01-1.28 mg L-1 waterborne Cu to investigate the developmental toxic effects. The results showed that Cu accumulation in the whole embryos presented a dose- and time-response increase while it decreased dramatically once hatching. Most of Cu accumulated in the chorion suggests that chorion is an effective barrier to Cu absorption. However, Cu that penetrated chorion and entered embryo still caused significant lethal and sublethal effects. Cu concentrations at >= 0.16 mg L-1 led to low hatchability, delayed hatching, high mortality, morphological abnormalities and increased egg size in the embryos. Heart beats and the total body length of the newly hatched larvae were significantly increased when exposed to >= 0.02 mg L-1. Cu exposure accelerated early development and promoted or delayed hatching of embryo. High Cu concentration (>= 0.16 mg L-1) exposure induced morphological abnormalities of embryo and larvae, particularly skeletal and vascular system abnormalities and reduction of pigmentation. The 30 d-LC50 for embryo development was 0.138 mg L-1 and 7d LC50 for larvae survival was 10.15 mg L-1, demonstrating that embryos were more sensitive to Cu than larvae. In summary, O. melastigma embryos development is highly sensitive to Cu exposure, and the sublethal effects occurred at low Cu concentration might be as potential biomarkers in marine fish. (C) 2020 Elsevier Ltd. All rights reserved. |
| 资助机构 | Strategic Priority Research Program of the Chinese Academy of SciencesChinese Academy of Sciences [XDA19060301]; National Natural Science Foundation of ChinaNational Natural Science Foundation of China (NSFC) [41922042]; Key Special Project for Introduced Talents Team of Southern Marine Science and Engineering Guangdong Laboratory (Guangzhou) [GML2019ZD0405]; Science and Technology Planning Project of Guangdong Province, China [2017B0303014052]; Innovation Academy of South China Sea Ecology and Environmental Engineering, Chinese Academy of Sciences [ISEE2018PY03] ; Strategic Priority Research Program of the Chinese Academy of SciencesChinese Academy of Sciences [XDA19060301]; National Natural Science Foundation of ChinaNational Natural Science Foundation of China (NSFC) [41922042]; Key Special Project for Introduced Talents Team of Southern Marine Science and Engineering Guangdong Laboratory (Guangzhou) [GML2019ZD0405]; Science and Technology Planning Project of Guangdong Province, China [2017B0303014052]; Innovation Academy of South China Sea Ecology and Environmental Engineering, Chinese Academy of Sciences [ISEE2018PY03] |
| 源URL | [http://ir.scsio.ac.cn/handle/344004/18434]  |
| 专题 | 南海海洋研究所_中科院海洋生物资源可持续利用重点实验室 |
| 作者单位 | 1.Southern Marine Sci & Engn Guangdong Lab Guangzho, Guangzhou, Peoples R China 2.Chinese Acad Sci, Inst South China Sea Ecol & Environm Engn, Guangzhou, Peoples R China 3.Chinese Acad Sci, South China Sea Inst Oceanol, Key Lab Trop Marine Bioresources & Ecol, Guangdong Prov Key Lab Appl Marine Biol, Guangzhou 510301, Peoples R China 4.Inner Mongolia Agr Univ, Coll Anim Sci, Hohhot 010018, Peoples R China |
| 推荐引用方式 GB/T 7714 | Wang, Rui-Fang,Zhu, Li-Mei,Zhang, Jun,et al. Developmental toxicity of copper in marine medaka (Oryzias melastigma) embryos and larvae[J]. CHEMOSPHERE,2020,247:125923. |
| APA | Wang, Rui-Fang.,Zhu, Li-Mei.,Zhang, Jun.,An, Xiao-Ping.,Yang, Yan-Ping.,...&Zhang, Li.(2020).Developmental toxicity of copper in marine medaka (Oryzias melastigma) embryos and larvae.CHEMOSPHERE,247,125923. |
| MLA | Wang, Rui-Fang,et al."Developmental toxicity of copper in marine medaka (Oryzias melastigma) embryos and larvae".CHEMOSPHERE 247(2020):125923. |
入库方式： OAI收割
来源：南海海洋研究所
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