Environmental estrogens and progestins disturb testis and brood pouch development with modifying transcriptomes in male-pregnancy lined seahorse Hippocampus erectus
文献类型：期刊论文
| 作者 | Qin, Geng3; Zhang, Yuan2; Zhang, Bo3; Zhang, Yanhong3; Liu, Yali3; Lin, Qiang2,3 |
| 刊名 | SCIENCE OF THE TOTAL ENVIRONMENT
 |
| 出版日期 | 2020 |
| 卷号 | 715页码:136840 |
| 关键词 | 17 alpha-ethynyl estradiol Progesterone Spermatogenesis Male pregnancy Seahorse |
| ISSN号 | 0048-9697 |
| DOI | 10.1016/j.scitotenv.2020.136840 |
| 英文摘要 | Exposure to environmental estrogens and progestins has contributed to adverse effects on the reproduction of many aquatic wildlife species. However, few reports have paid attention to fish species with specialized reproductive strategies, such as male-pregnancy seahorses. In this study, the potential effects on the behavior, gonad and brood pouch development, and transcriptomic profiles of lined seahorse I lippocarnpus erectus exposed to environmentally relevant concentrations of 17 alpha-ethynyl estradiol (EE2, 5 ng/L, 50 ng/L. 10 ng/L, 100 ng/L) or progesterone (P4) for 60 days were examined. Both EE2 and P4 significantly inhibited male brood pouch development by disrupting the extracellular matrix and basement membrane pathways. In addition, both EE2 and P4 impaired the expression of genes associated with spermatogenesis in the testis, and even caused male feminization. We suggest that seahorses be regarded as a sensitive indicator for evaluating the potential effects of endocrine disrupting chemical (EDC) pollution on aquatic biotic communities. (C) 2020 Elsevier B.V. All rights reserved. |
| 资助机构 | Key Research Program of Frontier Sciences of CAS [ZDBS-LY-DQC004]; National Natural Science Foundation of ChinaNational Natural Science Foundation of China (NSFC) [41825013, 41890853, 41706178]; National Key Research and Development Program [2016YFC1403003]; Key Special Project for Introduced Talents Team of Southern Marine Science and Engineering Guangdong Laboratory (Guangzhou) [GML2019ZD0407] ; Key Research Program of Frontier Sciences of CAS [ZDBS-LY-DQC004]; National Natural Science Foundation of ChinaNational Natural Science Foundation of China (NSFC) [41825013, 41890853, 41706178]; National Key Research and Development Program [2016YFC1403003]; Key Special Project for Introduced Talents Team of Southern Marine Science and Engineering Guangdong Laboratory (Guangzhou) [GML2019ZD0407] |
| 源URL | [http://ir.scsio.ac.cn/handle/344004/18439]  |
| 专题 | 南海海洋研究所_中科院海洋生物资源可持续利用重点实验室 |
| 作者单位 | 1.Univ Chinese Acad Sci, Beijing 100049, Peoples R China 2.Chinese Acad Sci, Inst South China Sea Ecol & Environm Engn, Guangzhou 510275, Peoples R China 3.Chinese Acad Sci, South China Sea Inst Oceanol, CAS Key Lab Trop Marine Bioresources & Ecol, Guangzhou 510275, Peoples R China |
| 推荐引用方式 GB/T 7714 | Qin, Geng,Zhang, Yuan,Zhang, Bo,et al. Environmental estrogens and progestins disturb testis and brood pouch development with modifying transcriptomes in male-pregnancy lined seahorse Hippocampus erectus[J]. SCIENCE OF THE TOTAL ENVIRONMENT,2020,715:136840. |
| APA | Qin, Geng,Zhang, Yuan,Zhang, Bo,Zhang, Yanhong,Liu, Yali,&Lin, Qiang.(2020).Environmental estrogens and progestins disturb testis and brood pouch development with modifying transcriptomes in male-pregnancy lined seahorse Hippocampus erectus.SCIENCE OF THE TOTAL ENVIRONMENT,715,136840. |
| MLA | Qin, Geng,et al."Environmental estrogens and progestins disturb testis and brood pouch development with modifying transcriptomes in male-pregnancy lined seahorse Hippocampus erectus".SCIENCE OF THE TOTAL ENVIRONMENT 715(2020):136840. |
入库方式： OAI收割
来源：南海海洋研究所
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