A new iron(III) chelator of coprogen-type siderophore from the deep-sea-derived fungus Mycosphaerella sp. SCSIO z059
文献类型：期刊论文
| 作者 | Huang Zhong-Hui; Liang Xiao; Qi Shu-Hua |
| 刊名 | CHINESE JOURNAL OF NATURAL MEDICINES
 |
| 出版日期 | 2020 |
| 卷号 | 18期号:4页码:243 |
| 关键词 | Deep-sea-derived fungus Mycosphaerella sp Iron(III) chelator Coprogen-type siderophore Cyclic amide Biofilm formation |
| ISSN号 | 2095-6975 |
| DOI | 10.1016/S1875-5364(20)30029-7 |
| 英文摘要 | Mycosphazine A (1), a new iron(III) chelator of coprogen-type siderophore, and mycosphamide A (2), a new cyclic amide benzoate, together with six known aryl amides (3-8), were isolated from the fermentation broth of the deep-sea-derived fungus Mycosphaerella sp. SCSIO z059. Alkaline hydrolysis of 1 afforded a new epimer of dimerum acid, mycosphazine B (1a), and a new bi-fusarinine-type siderophore, mycosphazine C (1b). The planar structures of the new compounds were elucidated by extensive spectroscopic data analysis. The absolute configurations of amino acid residues in 1a and 1b were determined by acid hydrolysis. And the absolute configuration of 2 was established by quantum chemical calculations of the electronic circular dichroism (ECD) spectra. Compound 1 is the first siderophore-Fe(III) chelator incorporating both L-ornithine and D-omithine unites. Compounds 3-8 were reported as natural products for the first time, and the H-1 and C-13 NMR data of 6 and 8 were assigned for the first time. Compounds 1 and 1a could greatly promote the biofilm formation of bacterium Bacillus amyloliquefaciens with the rate of about 249% and 524% at concentration of 100 mu g.mL(-1), respectively. |
| 资助机构 | Guangdong Provincial-level Special Funds for Promoting High-quality Economic Development [2020032]; Natural science foundation of Guangdong provinceNational Natural Science Foundation of Guangdong Province [2017A030313235]; Key Special Project for Introduced Talents Team of Southern Marine Science and Engineering Guangdong Laboratory (Guangzhou) [GML2019ZD0406]; National Natural Science Foundation of ChinaNational Natural Science Foundation of China (NSFC) [81673326] ; Guangdong Provincial-level Special Funds for Promoting High-quality Economic Development [2020032]; Natural science foundation of Guangdong provinceNational Natural Science Foundation of Guangdong Province [2017A030313235]; Key Special Project for Introduced Talents Team of Southern Marine Science and Engineering Guangdong Laboratory (Guangzhou) [GML2019ZD0406]; National Natural Science Foundation of ChinaNational Natural Science Foundation of China (NSFC) [81673326] |
| 源URL | [http://ir.scsio.ac.cn/handle/344004/18462]  |
| 专题 | 南海海洋研究所_中科院海洋生物资源可持续利用重点实验室 |
| 作者单位 | 1.Liang Xiao 2.Southern Marine Sci & Engn Guangdong Lab, Guangzhou 511458, Peoples R China 3.Chinese Acad Sci, Inst South China Sea Ecol & Environm Engn, South China Sea Inst Oceanol, CAS Key Lab Trop Marine Bioresources & Ecol, Guangzhou 510301, Peoples R China 4.[Huang Zhong-Hui |
| 推荐引用方式 GB/T 7714 | Huang Zhong-Hui,Liang Xiao,Qi Shu-Hua. A new iron(III) chelator of coprogen-type siderophore from the deep-sea-derived fungus Mycosphaerella sp. SCSIO z059[J]. CHINESE JOURNAL OF NATURAL MEDICINES,2020,18(4):243, 249. |
| APA | Huang Zhong-Hui,Liang Xiao,&Qi Shu-Hua.(2020).A new iron(III) chelator of coprogen-type siderophore from the deep-sea-derived fungus Mycosphaerella sp. SCSIO z059.CHINESE JOURNAL OF NATURAL MEDICINES,18(4),243. |
| MLA | Huang Zhong-Hui,et al."A new iron(III) chelator of coprogen-type siderophore from the deep-sea-derived fungus Mycosphaerella sp. SCSIO z059".CHINESE JOURNAL OF NATURAL MEDICINES 18.4(2020):243. |
入库方式： OAI收割
来源：南海海洋研究所
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