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New quinoline alkaloid and bisabolane-type sesquiterpenoid derivatives from the deep-sea-derived fungus Aspergillus sp. SCSI006786

文献类型：期刊论文

作者Pang, Xiaoyan1,2; Lin, Xiuping1; Zhou, Xuefeng1; Yang, Bin1; Tian, Xinpeng1; Wang, Junfeng1; Xu, Shihai; Liu, Yonghong1
刊名FITOTERAPIA
出版日期2020
卷号140页码:104406
关键词Deep-sea-derived fungus Aspergillus sp. Secondary metabolites Antibacterial
ISSN号0367-326X
DOI10.1016/j.fitote.2019.104406
英文摘要One new quinoline alkaloid (1), two new bisabolane-type sesquiterpene derivatives (2 and 3), and a new natural product (4) along with ten known compounds (514) were isolated from the deep sea-derived fungus Aspergillus sp. SCSI006786 which cultured on solid rice medium. Three new structures were elucidated by analysis of 1D/2D NMR data and HR-ESI-MS. The absolute configurations of 2 and 3 were established by comparison of the experimental and reported ECD values. Compounds 11-13 exhibited moderate selective inhibitory activities against the tested pathogenic bacteria with MIC values among 3.13-12.5 mu g/mL.
资助机构National Key Research and Development Program of China [2018YFC0310900]; National Natural Science Foundation of ChinaNational Natural Science Foundation of China (NSFC) [21172230, 21672084, 21772210, 31270402, 41476135, 41776169, 41876145]; Strategic Priority Research Program of the Chinese Academy of SciencesChinese Academy of Sciences [XDA11030403]; Guangdong Province Public Welfare Research and Capacity Building Project [2016A020222010]; Pearl River S&T Nova Program of Guangzhou [201710010136] ; National Key Research and Development Program of China [2018YFC0310900]; National Natural Science Foundation of ChinaNational Natural Science Foundation of China (NSFC) [21172230, 21672084, 21772210, 31270402, 41476135, 41776169, 41876145]; Strategic Priority Research Program of the Chinese Academy of SciencesChinese Academy of Sciences [XDA11030403]; Guangdong Province Public Welfare Research and Capacity Building Project [2016A020222010]; Pearl River S&T Nova Program of Guangzhou [201710010136]
源URL[http://ir.scsio.ac.cn/handle/344004/18523]  
专题南海海洋研究所_中科院海洋生物资源可持续利用重点实验室
作者单位1.Jinan Univ, Coll Chem & Mat Sci, Guangzhou 510632, Peoples R China
2.Chinese Acad Sci, South China Sea Inst Oceanol, Guangdong Key Lab Marine Mat, CAS Key Lab Trop Marine Rioresources & Ecol, Guangzhou 510301, Peoples R China
3.Jinan Univ, Coll Pharm, Guangzhou 510632, Peoples R China
推荐引用方式
GB/T 7714		 Pang, Xiaoyan,Lin, Xiuping,Zhou, Xuefeng,et al. New quinoline alkaloid and bisabolane-type sesquiterpenoid derivatives from the deep-sea-derived fungus Aspergillus sp. SCSI006786[J]. FITOTERAPIA,2020,140:104406.
APA Pang, Xiaoyan.,Lin, Xiuping.,Zhou, Xuefeng.,Yang, Bin.,Tian, Xinpeng.,...&Liu, Yonghong.(2020).New quinoline alkaloid and bisabolane-type sesquiterpenoid derivatives from the deep-sea-derived fungus Aspergillus sp. SCSI006786.FITOTERAPIA,140,104406.
MLA Pang, Xiaoyan,et al."New quinoline alkaloid and bisabolane-type sesquiterpenoid derivatives from the deep-sea-derived fungus Aspergillus sp. SCSI006786".FITOTERAPIA 140(2020):104406.

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来源：南海海洋研究所

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