三株海洋来源真菌次生代谢产物及其生物活性研究
文献类型：学位论文
| 作者 | MUHAMMAD AMIN |
| 答辩日期 | 2019 |
| 授予单位 | 南海海洋研究所 |
| 导师 | 漆淑华 |
| 关键词 | 柳珊瑚共附生真菌，Penicillium chrysogenum SCSIO 00258，Aspergillus sydowii SCSIO 00305，沉积物来源真菌，Cladosporium cladosporioides SCSIO z015 |
| 学位名称 | 博士 |
| 学位专业 | 海洋化学 |
| 其他题名 | Studies on the Secondary Metabolites of Three Marine-Derived Fungal Strains and Their Bioactivities |
| 英文摘要 | Marine ecosystem possesses all kind of microorganisms for its special and unique environment. These marine microorganisms have their unique, and complex metabolic pathways and genetic background, and can produce distinct metabolites with novel structures, and continue to be an important source of bioactive lead compounds. In this dissertation three marine-derived fungi, including, two fungal stains, Penicillium chrysogenum SCSIO 00258 and Aspergillus sydowii SCSIO 00305 were collected from deep-sea gorgonian while the strain SCSIO z015 were collected in Okinawa Trough from deep-sea gorgonian South China Sea, , and the fungal strain C. cladosporioides SCSIO z015 was isolated from the deep-sea sediments in Okinawa Trough South China Sea. These fungal strains were selected as aim strains for further investigation of their secondary metabolites. As a result, seventy-one compounds were isolated and structurally elucidated from the cultural extracts of these three fungal strains, including 8 of them were new compounds. Some of the isolated compounds were evaluated their anti-biofilm, cytotoxicity, and DPPH scavenging activities. |
| 源URL | [http://ir.scsio.ac.cn/handle/344004/18145]  |
| 专题 | 南海海洋研究所_学位论文（博士） |
| 推荐引用方式 GB/T 7714 | MUHAMMAD AMIN. 三株海洋来源真菌次生代谢产物及其生物活性研究[D]. 南海海洋研究所. 2019. |
入库方式： OAI收割
来源：南海海洋研究所
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