Bioreactor synergy with 3D scaffolds: New era for stem cells culture
文献类型：期刊论文
| 作者 | Yi, Tianqi2; Huang, Shaoxiong2; Liu, Guiting2; Li, Tiancheng2; Kang, Yang3; Luo, Yuxi2; Wu, Jun1,2 |
| 刊名 | ACS Applied Bio Materials
 |
| 出版日期 | 2018 |
| 卷号 | 1期号:2页码:193-209 |
| ISSN号 | 2576-6422 |
| DOI | 10.1021/acsabm.8b00057 |
| 产权排序 | 2 |
| 文献子类 | Article |
| 英文摘要 | Because of unparalleled advantages over other cells, stem cells are widely used in genetic diagnosis, drug delivery, and regenerative medicine. However, because the content of stem cells in the organism is far from satisfactory, it is of great significance of stem cells to in vitro proliferation and differentiation. However, many stem cell cultures have low expansion efficiency and stem cells lose their value-adding ability and differentiation ability after many generations of culture. To solve these problems, people hope to more realistically simulate the microenvironment in which stem cells grow in vivo. Cell scaffolds gradually evolve from 2D structures to 3D structures. The addition of growth factors influences cell behavior from internal biochemical conditions and the development of smart bioreactors gradually make progress to more precise regulate the external conditions of stem cell. In this paper, the key factors for constructing the microenvironment of stem cell growth were analyzed, and we reviewed the application of bioreactors and 3D scaffolds in stem cell cultivation. Finally, this paper indicated the development directions of stem cell culture in vitro. |
| 语种 | 英语 |
| 源URL | [http://210.75.237.14/handle/351003/30396]  |
| 专题 | 国家天然药物工程技术研究中心_天然产物研究 成都生物研究所_天然产物研究 生物多样性与生态系统服务领域_中国科学院山地生态恢复与生物资源利用重点实验室 |
| 作者单位 | 1.Key Laboratory of Polymer Composites and Functional Materials of Ministry of Education, Sun Yat-sen University, Guangzhou; 510006, China 2.Key Laboratory of Sensing Technology and Biomedical Instrument of Guangdong Province, School of Biomedical Engineering, Sun Yat-sen University, Guangzhou; 510006, China; 3.Key Laboratory of Mountain Ecological Restoration and Bioresource Utilization, Chengdu Institute of Biology, Chinese Academy of Sciences, Chengdu; 610041, China; |
| 推荐引用方式 GB/T 7714 | Yi, Tianqi,Huang, Shaoxiong,Liu, Guiting,et al. Bioreactor synergy with 3D scaffolds: New era for stem cells culture[J]. ACS Applied Bio Materials,2018,1(2):193-209. |
| APA | Yi, Tianqi.,Huang, Shaoxiong.,Liu, Guiting.,Li, Tiancheng.,Kang, Yang.,...&Wu, Jun.(2018).Bioreactor synergy with 3D scaffolds: New era for stem cells culture.ACS Applied Bio Materials,1(2),193-209. |
| MLA | Yi, Tianqi,et al."Bioreactor synergy with 3D scaffolds: New era for stem cells culture".ACS Applied Bio Materials 1.2(2018):193-209. |
入库方式： OAI收割
来源：成都生物研究所
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