Xylastriasan A, a new cytochalasan from the fungus Xylaria striata
文献类型：期刊论文
| 作者 | Lei, Chuan-Wen1; Yang, Zhi-Qin1; Zeng, Yan-Ping1; Zhou, Yun1; Huang, Yi1; He, Xin-Sheng1; Li, Guo-You2; Yuan, Xiao-Hong1 |
| 刊名 | NATURAL PRODUCT RESEARCH
 |
| 出版日期 | 2018 |
| 卷号 | 32期号:1页码:7-13 |
| ISSN号 | 1478-6419 |
| 关键词 | Xylaria striata cytochalasan ergosterol cytotoxic hypnotic activity |
| DOI | 10.1080/14786419.2017.1324959 |
| 产权排序 | 2 |
| 文献子类 | Article |
| 英文摘要 | Xylastriasan A (1), a new cytochalasan alkaloid with a rare 5/6/6/5/6 pentacyclic skeleton, and ergosterol (2) were isolated from the ethanol extract of fruiting bodies of the fungus Xylaria striata. Their structures were determined by analysis of their spectroscopic data. Compound 1 exhibited weak cytotoxic activity against HEPG2, B16 and A549 cell lines with IC50 values of 93.61, 85.61 and 91.58 mu M, respectively. Ergosterol (2) potentiated pentobarbital-induced sleep by not only increasing the number of falling asleep and prolonging sleeping time but also reducing sleep latency at a dosage of 5 mg/kg. [GRAPHICS] . |
| URL标识 | 查看原文 |
| WOS关键词 | CYTOTOXIC CONSTITUENTS ; ENDOPHYTIC FUNGUS ; SPICARIA-ELEGANS ; MICE |
| WOS研究方向 | Chemistry ; Pharmacology & Pharmacy |
| 语种 | 英语 |
| 出版者 | TAYLOR & FRANCIS LTD |
| WOS记录号 | WOS:000417625600002 |
| 源URL | [http://210.75.237.14/handle/351003/30364]  |
| 专题 | 环境治理与食品安全领域_应用与环境微生物研究 环境治理与食品安全领域_中国科学院环境与应用微生物重点实验室 |
| 作者单位 | 1.Southwest Univ Sci & Technol, Sch Life Sci & Engn, Mianyang, Peoples R China; 2.Chinese Acad Sci, Chengdu Inst Biol, Key Lab Environm & Appl Microbiol, Chengdu, Sichuan, Peoples R China |
| 推荐引用方式 GB/T 7714 | Lei, Chuan-Wen,Yang, Zhi-Qin,Zeng, Yan-Ping,et al. Xylastriasan A, a new cytochalasan from the fungus Xylaria striata[J]. NATURAL PRODUCT RESEARCH,2018,32(1):7-13. |
| APA | Lei, Chuan-Wen.,Yang, Zhi-Qin.,Zeng, Yan-Ping.,Zhou, Yun.,Huang, Yi.,...&Yuan, Xiao-Hong.(2018).Xylastriasan A, a new cytochalasan from the fungus Xylaria striata.NATURAL PRODUCT RESEARCH,32(1),7-13. |
| MLA | Lei, Chuan-Wen,et al."Xylastriasan A, a new cytochalasan from the fungus Xylaria striata".NATURAL PRODUCT RESEARCH 32.1(2018):7-13. |
入库方式： OAI收割
来源：成都生物研究所
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