Antioxidant and Hepatoprotective Effects of Methanolic Extracts of Zilla spinosa and Hammada elegans Against Carbon Tetrachloride-induced Hepatotoxicity in Rats
文献类型：期刊论文
| 作者 | Ullah, Riaz3,4; Alsaid, Mansour S.3; Shahat, Abdelaaty A.1,3; Naser, Almoqbil Abdulaziz3; Al-Mishari, Abdullah A.3; Adnan, Muhammad5; Tariq, Akash2,7 |
| 刊名 | OPEN CHEMISTRY
 |
| 出版日期 | 2018 |
| 卷号 | 16期号:1页码:133-140 |
| 关键词 | Z. spinosa H. elegans hepatoprotective |
| ISSN号 | 2391-5420 |
| DOI | 10.1515/chem-2018-0021 |
| 产权排序 | 5 |
| 文献子类 | Article |
| 英文摘要 | The detoxification, metabolism, and excretion of various endogenous and exogenous materials occur mainly in the liver. Liver diseases are a global concern, and classified as chronic hepatitis, cirrhosis, and hepatosis. The development of safe hepatoprotective agents remains an unmet need. Therefore, we investigated the antioxidant effects of methanolic and n-hexane fractions of Zilla spinosa (ZSM and ZSH, respectively) and Hammada elegans (HEM and HEH, respectively) against carbon tetrachloride (CCl4)-induced liver toxicity in rats. Antioxidant activity was studied by the 2,2-diphenyl-1-picrylhydrazyl (DPPH) assay. The rats were divided into 11 groups (n=6)-group 1 (control), group 2 (CCl4 only), group 3 (CCl4 + silymarin 10 mg/kg), group 4 (CCl4 + HEM 250 mg/kg), group 5 (CCl4 + HEM 500 mg/kg), group 6 (CCl4 + HEH 250 mg/kg), group 7 (CCl4 + HEH 500 mg/kg), group 8 (CCl4 + ZSM 250 mg/kg), |
| 学科主题 | Chemistry |
| URL标识 | 查看原文 |
| WOS关键词 | LIVER ; DISEASE |
| WOS研究方向 | Chemistry |
| 语种 | 英语 |
| WOS记录号 | WOS:000427650900010 |
| 出版者 | DE GRUYTER POLAND SP ZOO |
| 源URL | [http://210.75.237.14/handle/351003/30383]  |
| 专题 | 生物多样性与生态系统服务领域_生态系统恢复与生物多样性保育四川省重点实验室 生物多样性与生态系统服务领域_中国科学院山地生态恢复与生物资源利用重点实验室 生物多样性与生态系统服务领域_生态研究 |
| 作者单位 | 1.Res Ctr, Phytochem Dept, 33 El Bohouth St,POB12622, Giza, Egypt; 2.Chinese Acad Sci, Chengdu Inst Biol, Key Lab Mt Ecol Restorat & Bioresource Utilizat f, Chengdu 610041, Sichuan, Peoples R China; 3.Department of Pharmacognosy and Medicinal, Aromatic & Poisonous Plants Research Center MAPPRC),College of Pharmacy, King Saud University, P.O. Box 2457, Riyadh 11451, Saudi Arabia; 4.Govt Coll Ara Khel FR Kohat KPK Pakistan, Dept Chem, Kohat, Pakistan; 5.Kohat Univ Sci & Technol KUST KPK Pakistan, Dept Bot, Kohat, Pakistan; 6.Univ Chinese Acad Sci, Beijing, Peoples R China 7.Chinese Acad Sci, Chengdu Inst Biol, Ecol Restorat Biodivers Conservat Key Lab Sichuan, Chengdu 610041, Sichuan, Peoples R China; |
| 推荐引用方式 GB/T 7714 | Ullah, Riaz,Alsaid, Mansour S.,Shahat, Abdelaaty A.,et al. Antioxidant and Hepatoprotective Effects of Methanolic Extracts of Zilla spinosa and Hammada elegans Against Carbon Tetrachloride-induced Hepatotoxicity in Rats[J]. OPEN CHEMISTRY,2018,16(1):133-140. |
| APA | Ullah, Riaz.,Alsaid, Mansour S..,Shahat, Abdelaaty A..,Naser, Almoqbil Abdulaziz.,Al-Mishari, Abdullah A..,...&Tariq, Akash.(2018).Antioxidant and Hepatoprotective Effects of Methanolic Extracts of Zilla spinosa and Hammada elegans Against Carbon Tetrachloride-induced Hepatotoxicity in Rats.OPEN CHEMISTRY,16(1),133-140. |
| MLA | Ullah, Riaz,et al."Antioxidant and Hepatoprotective Effects of Methanolic Extracts of Zilla spinosa and Hammada elegans Against Carbon Tetrachloride-induced Hepatotoxicity in Rats".OPEN CHEMISTRY 16.1(2018):133-140. |
入库方式： OAI收割
来源：成都生物研究所
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