Phylogenomic analysis demonstrates a pattern of rare and long-lasting concerted evolution in prokaryotes
文献类型：期刊论文
| 作者 | Wang, Sishuo1,4; Chen, Youhua2,3 |
| 刊名 | COMMUNICATIONS BIOLOGY
 |
| 出版日期 | 2018 |
| 卷号 | 1页码:12 |
| ISSN号 | 2399-3642 |
| DOI | 10.1038/s42003-018-0014-x |
| 产权排序 | 3 |
| 文献子类 | Article |
| 英文摘要 | Concerted evolution, where paralogs in the same species show higher sequence similarity to each other than to orthologs in other species, is widely found in many species. However, cases of concerted evolution that last for hundreds of millions of years are very rare. By genome-wide analysis of a broad selection of prokaryotes, we provide strong evidence of recurrent concerted evolution in 26 genes, most of which have lasted more than similar to 500 million years. We find that most concertedly evolving genes are key members of important pathways, and encode proteins from the same complexes and/or pathways, suggesting coevolution of genes via concerted evolution to maintain gene balance. We also present LRCE-DB, a comprehensive online repository of long-lasting concerted evolution. Collectively, our study reveals that although most duplicated genes may diverge in sequence over a long period, on rare occasions this constraint can be breached, leading to unexpected long-lasting concerted evolution in a recurrent manner. |
| URL标识 | 查看原文 |
| WOS关键词 | GENE CONVERSION ; DOSAGE-SENSITIVITY ; AMMONIA MONOOXYGENASE ; DEATH EVOLUTION ; DUPLICATION ; DIVERGENCE ; MECHANISM ; SELECTION ; MUTAGENESIS ; SOFTWARE |
| WOS研究方向 | Life Sciences & Biomedicine - Other Topics ; Science & Technology - Other Topics |
| 语种 | 英语 |
| WOS记录号 | WOS:000461126500012 |
| 出版者 | NATURE PUBLISHING GROUP |
| 源URL | [http://210.75.237.14/handle/351003/30395]  |
| 专题 | 食品安全与环境治理领域_中国科学院环境与应用微生物重点实验室 |
| 作者单位 | 1.Univ British Columbia, Beaty Biodivers Res Ctr, 2212 Main Mall, Vancouver, BC V6T 1Z4, Canada; 2.Univ Alberta, Fac Agr Life & Environm Sci, Dept Renewable Resources, Edmonton, AB T6G 2H1, Canada 3.Chinese Acad Sci, Chengdu Inst Biol, Chengdu 610000, Sichuan, Peoples R China; 4.Univ British Columbia, Fac Sci, Dept Bot, 3529-6270 Univ Blvd, Vancouver, BC V6T 1Z4, Canada; |
| 推荐引用方式 GB/T 7714 | Wang, Sishuo,Chen, Youhua. Phylogenomic analysis demonstrates a pattern of rare and long-lasting concerted evolution in prokaryotes[J]. COMMUNICATIONS BIOLOGY,2018,1:12. |
| APA | Wang, Sishuo,&Chen, Youhua.(2018).Phylogenomic analysis demonstrates a pattern of rare and long-lasting concerted evolution in prokaryotes.COMMUNICATIONS BIOLOGY,1,12. |
| MLA | Wang, Sishuo,et al."Phylogenomic analysis demonstrates a pattern of rare and long-lasting concerted evolution in prokaryotes".COMMUNICATIONS BIOLOGY 1(2018):12. |
入库方式： OAI收割
来源：成都生物研究所
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