Direct and highly stereoselective synthesis of quinolizidine iminosugars promoted by L-proline-Et3N
文献类型：期刊论文
| 作者 | Yuan, Wen1,2,3; Pan, Yang1,3; Zhang, Xiaoke1,3; Liang, Peng1,3; Zhang, Jichao1,3; Jiao, Wei3; Shao, Huawu3 |
| 刊名 | ORGANIC & BIOMOLECULAR CHEMISTRY
 |
| 出版日期 | 2019-12-21 |
| 卷号 | 16期号:47页码:9230-9236 |
| ISSN号 | 1477-0520 |
| DOI | 10.1039/c8ob01953crsc.li/obc |
| 产权排序 | 1 |
| 文献子类 | Article |
| 英文摘要 | A mild and effective method for the synthesis of polyhydroxylated quinolizidine iminosugars is described. The Mannich-type reaction of iminosugar C-glycosides with aldehyde in the presence of L-proline-Et3N provides polyhydroxylated quinolizidine iminosugars, and desired products as the potential glucosidase inhibitors were obtained in good to excellent yields with excellent stereoselectivity. |
| URL标识 | 查看原文 |
| WOS关键词 | GLYCOSIDASE INHIBITORS ; ASYMMETRIC-SYNTHESIS ; POLYHYDROXYLATED QUINOLIZIDINES ; 1,2-CYCLOPROPANATED SUGARS ; 1,3-DIPOLAR CYCLOADDITION ; INDOLIZIDINE ; DERIVATIVES ; EFFICIENT ; CONCISE ; CASTANOSPERMINE |
| WOS研究方向 | Chemistry |
| 语种 | 英语 |
| WOS记录号 | WOS:000452321100019 |
| 出版者 | ROYAL SOC CHEMISTRY |
| 源URL | [http://210.75.237.14/handle/351003/30081]  |
| 专题 | 国家天然药物工程技术研究中心_天然产物研究 |
| 作者单位 | 1.Sichuan Coll Tradit Chinese Med, Mianyang, Sichuan, Peoples R China; 2.Univ Chinese Acad Sci, Beijing, Peoples R China 3.Chinese Acad Sci, Chengdu Inst Biol, Nat Prod Res Ctr, Chengdu, Sichuan, Peoples R China; |
| 推荐引用方式 GB/T 7714 | Yuan, Wen,Pan, Yang,Zhang, Xiaoke,et al. Direct and highly stereoselective synthesis of quinolizidine iminosugars promoted by L-proline-Et3N[J]. ORGANIC & BIOMOLECULAR CHEMISTRY,2019,16(47):9230-9236. |
| APA | Yuan, Wen.,Pan, Yang.,Zhang, Xiaoke.,Liang, Peng.,Zhang, Jichao.,...&Shao, Huawu.(2019).Direct and highly stereoselective synthesis of quinolizidine iminosugars promoted by L-proline-Et3N.ORGANIC & BIOMOLECULAR CHEMISTRY,16(47),9230-9236. |
| MLA | Yuan, Wen,et al."Direct and highly stereoselective synthesis of quinolizidine iminosugars promoted by L-proline-Et3N".ORGANIC & BIOMOLECULAR CHEMISTRY 16.47(2019):9230-9236. |
入库方式： OAI收割
来源：成都生物研究所
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