Assessment of the antitumor activity of a cyclopalladated ferrocene compound assisted by a dual-targeting drug delivery system
文献类型：期刊论文
| 作者 | Gong, Guidong1; Cao, Yuan1; Qian, Hongyun1; Zhou, Yangyang1; Zhao, Haihang1; Li, Ling1; Wang, Fei2; Zhao, Gang1 |
| 刊名 | CHEMICAL COMMUNICATIONS
 |
| 出版日期 | 2019-08-04 |
| 卷号 | 54期号:60页码:8312-8315 |
| ISSN号 | 1359-7345 |
| DOI | 10.1039/c8cc03308k |
| 产权排序 | 2 |
| 文献子类 | Article |
| 英文摘要 | One cyclopalladated ferrocene compound CP was synthesized, which showed a good cell cytotoxicity. Assisted by a dual-targeting drug delivery system, the anticancer activity of CP to MDA-MB-468 remained unchanged, but the toxicity to non-tumorigenic cell line NIH3T3 was remarkably reduced. This provided a new path for the development of cyclopalladated ferrocene as an antitumor drug candidate. |
| 学科主题 | Chemistry |
| URL标识 | 查看原文 |
| WOS关键词 | MITOCHONDRIAL-MEMBRANE ; RECENT PROGRESS ; CANCER-CELLS ; DERIVATIVES ; APOPTOSIS ; REDOX ; PERMEABILIZATION ; NANOTECHNOLOGY ; NANOPARTICLE ; HYALURONAN |
| WOS研究方向 | Chemistry |
| 语种 | 英语 |
| WOS记录号 | WOS:000439702200002 |
| 出版者 | ROYAL SOC CHEMISTRY |
| 源URL | [http://210.75.237.14/handle/351003/30187]  |
| 专题 | 国家天然药物工程技术研究中心_天然产物研究 国家天然药物工程技术研究中心_天然药物与临床转化重点实验室 |
| 作者单位 | 1.Sichuan Univ, Coll Chem Engn, Chengdu 610064, Sichuan, Peoples R China; 2.Chinese Acad Sci, Chengdu Inst Biol, Key Lab Nat Med & Clin Translat, Chengdu 610041, Sichuan, Peoples R China |
| 推荐引用方式 GB/T 7714 | Gong, Guidong,Cao, Yuan,Qian, Hongyun,et al. Assessment of the antitumor activity of a cyclopalladated ferrocene compound assisted by a dual-targeting drug delivery system[J]. CHEMICAL COMMUNICATIONS,2019,54(60):8312-8315. |
| APA | Gong, Guidong.,Cao, Yuan.,Qian, Hongyun.,Zhou, Yangyang.,Zhao, Haihang.,...&Zhao, Gang.(2019).Assessment of the antitumor activity of a cyclopalladated ferrocene compound assisted by a dual-targeting drug delivery system.CHEMICAL COMMUNICATIONS,54(60),8312-8315. |
| MLA | Gong, Guidong,et al."Assessment of the antitumor activity of a cyclopalladated ferrocene compound assisted by a dual-targeting drug delivery system".CHEMICAL COMMUNICATIONS 54.60(2019):8312-8315. |
入库方式： OAI收割
来源：成都生物研究所
浏览0
下载0
收藏0
其他版本
除非特别说明，本系统中所有内容都受版权保护，并保留所有权利。