Comparative transcriptome analysis of scaled and scaleless skins in Gymnocypris eckloni provides insights into the molecular mechanism of scale degeneration
文献类型：期刊论文
| 作者 | Feng,Xiu1; Jia,Yintao1; Zhu,Ren1; Li,Kemao2; Guan,Zhongzhi2; Chen,Yifeng1 |
| 刊名 | BMC Genomics
 |
| 出版日期 | 2020-11-27 |
| 卷号 | 21期号:1 |
| 关键词 | Gymnocypris eckloni Transcriptome Skin Scale degeneration |
| DOI | 10.1186/s12864-020-07247-w |
| 通讯作者 | Chen,Yifeng(chenyf@ihb.ac.cn) |
| 英文摘要 | AbstractBackgroundThe scale degeneration is thought to be related to the adaptation to the extreme environment with cold climate and high-altitude in schizothoracine fishes. Gymnocypris eckloni, a schizothoracine fish living in plateau waters with the elevation above 2500?m, is nearly esquamate and only covered with shoulder scales and anal scales, making it a good model species to study the molecular mechanism of scale degeneration.ResultsThe transcriptomes of shoulder scaled skins (SSS), anal scaled skins (ASS) and scaleless skins (NSS) were sequenced and analyzed in G. eckloni at the age of 1 year. Histological examination showed that shoulder scale had completed its differentiation and anal scale just initiated the differentiation. A total of 578,046 unigenes were obtained from the transcriptomes, with 407,799 unigenes annotated in public databases. A total of 428 and 142 differentially expressed unigenes (DEUs) were identified between SSS and NSS, and between ASS and NSS, respectively, with 45 DEUs that were overlapped. Annotation analysis indicated that these DEUs were mainly enriched in Gene Ontology (GO) terms and KEGG pathways associated with bone and muscle formation, such as myofibril, contractile fiber, cytoskeletal protein binding, muscle structure development, cardiac muscle contraction, hypertrophic cardiomyopathy (HCM) and calcium signaling pathway.ConclusionsOur results would provide insights into the molecular mechanisms of scale degeneration in G. eckloni and other congeneric fishes. In addition, the transcriptome data provides candidate genes and markers for future studies. |
| 语种 | 英语 |
| WOS记录号 | BMC:10.1186/S12864-020-07247-W |
| 出版者 | BioMed Central |
| 源URL | [http://ir.ihb.ac.cn/handle/342005/39236]  |
| 专题 | 水生生物研究所_水生生物多样性与资源保护研究中心_期刊论文 |
| 通讯作者 | Chen,Yifeng |
| 作者单位 | 1.Chinese Academy of Sciences; Institute of Hydrobiology 2.QingHai Provincial Fishery Environmental Monitoring Center |
| 推荐引用方式 GB/T 7714 | Feng,Xiu,Jia,Yintao,Zhu,Ren,et al. Comparative transcriptome analysis of scaled and scaleless skins in Gymnocypris eckloni provides insights into the molecular mechanism of scale degeneration[J]. BMC Genomics,2020,21(1). |
| APA | Feng,Xiu,Jia,Yintao,Zhu,Ren,Li,Kemao,Guan,Zhongzhi,&Chen,Yifeng.(2020).Comparative transcriptome analysis of scaled and scaleless skins in Gymnocypris eckloni provides insights into the molecular mechanism of scale degeneration.BMC Genomics,21(1). |
| MLA | Feng,Xiu,et al."Comparative transcriptome analysis of scaled and scaleless skins in Gymnocypris eckloni provides insights into the molecular mechanism of scale degeneration".BMC Genomics 21.1(2020). |
入库方式： OAI收割
来源：水生生物研究所
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