Evaluating toxicity impacts of environmental exposed chromium on small Indian mongoose (Urva auropunctatus) hematological, biochemical and histopathological functioning
文献类型：期刊论文
| 作者 | Andleeb, Shaista4; Ahmad, Zulfiqar1; Mahmood, Tariq5; Bao, Shenxu4; Saeed, Abdullah Arif2; Jha, Sunil Kumar3 |
| 刊名 | CHEMOSPHERE
 |
| 出版日期 | 2020-11-01 |
| 卷号 | 259页码:9 |
| 关键词 | Chromium toxicity Hematology Nephrotoxicity Hepatotoxicity Small indian mongoose |
| ISSN号 | 0045-6535 |
| DOI | 10.1016/j.chemosphere.2020.127485 |
| 通讯作者 | Bao, Shenxu(sxbao@whut.edu.cn) |
| 英文摘要 | Sub-lethal toxic impacts of chromium on hematological, biochemical and histological parameters were analyzed in the female small Indian mongoose (Urva auropuctatus) residing contaminated environment of tannery industry. Chromium bioaccumulation in the blood, liver and kidney tissue of the exposed mongooses was found elevated compared to the control mongooses' tissues. Total body weight (75.7%), liver weight (83.6%) as well as HSI (68.1%), RSI (86.2%) and the platelets counts (59.7%) were found significantly elevated, with significantly reduced RBCs (59.6%), and WBCs (64%). LFT and RFT were also found abnormal, moreover, the histopathological injuries had been distinct inside the kidney (>75%) and hepatic (>75%) tissues of exposed animals. Shrinkage and vacuolization (> 75%) inside the hepatocyte expanded sinusoidal spaces and nuclear pyknosis (>75%) was evident within the hepatic tissue. Hypertrophy of epithelial cells of renal tubules and inter-renal cells of the head kidney with a reduction in tubular lumens (>75%) and vacuolization of tubules were witnessed within the kidney section. Atrophy inside the kidney inter-renal cells, glomeruli compression within the Bowman's capsules (>75%) following the necrosis in hematopoietic tissues were found in exposed animals. The present findings indicate that chronic exposure to chromium induces severe anemia, decreased serum protein concentration, hepatic and renal tissue histopathology, impairing the vital capabilities of liver, metabolic regulation, excretion, and stress homeostasis maintenance of which within the long-run may posture a severe risk to animal well-being then distress their inhabitants. (C) 2020 Elsevier Ltd. All rights reserved. |
| WOS关键词 | FRESH-WATER FISH ; OXIDATIVE STRESS ; HEXAVALENT CHROMIUM ; INDUCED NEPHROTOXICITY ; GAMBUSIA-AFFINIS ; LIVER ; APOPTOSIS ; GILL ; DISTURBANCES ; MOSQUITOFISH |
| WOS研究方向 | Environmental Sciences & Ecology |
| 语种 | 英语 |
| WOS记录号 | WOS:000566573600089 |
| 出版者 | PERGAMON-ELSEVIER SCIENCE LTD |
| 源URL | [http://ir.ihb.ac.cn/handle/342005/38662]  |
| 专题 | 水生生物研究所_其他_期刊论文 |
| 通讯作者 | Bao, Shenxu |
| 作者单位 | 1.Chinese Acad Sci, Inst Hydrobiol, Key Lab Algal Biol, Wuhan 430072, Peoples R China 2.Univ Vet & Anim Sci, Dept Physiol, Lahore 54000, Pakistan 3.Univ Informat Technol & Management, Fac Informat Technol, Rzeszow, Poland 4.Wuhan Univ Technol, Sch Resources & Environm Engn, 122 Luoshi Rd, Wuhan 430070, Hubei, Peoples R China 5.PMAS Arid Agr Univ Rawalpindi, Dept Wildlife Management, Rawalpindi 46300, Pakistan |
| 推荐引用方式 GB/T 7714 | Andleeb, Shaista,Ahmad, Zulfiqar,Mahmood, Tariq,et al. Evaluating toxicity impacts of environmental exposed chromium on small Indian mongoose (Urva auropunctatus) hematological, biochemical and histopathological functioning[J]. CHEMOSPHERE,2020,259:9. |
| APA | Andleeb, Shaista,Ahmad, Zulfiqar,Mahmood, Tariq,Bao, Shenxu,Saeed, Abdullah Arif,&Jha, Sunil Kumar.(2020).Evaluating toxicity impacts of environmental exposed chromium on small Indian mongoose (Urva auropunctatus) hematological, biochemical and histopathological functioning.CHEMOSPHERE,259,9. |
| MLA | Andleeb, Shaista,et al."Evaluating toxicity impacts of environmental exposed chromium on small Indian mongoose (Urva auropunctatus) hematological, biochemical and histopathological functioning".CHEMOSPHERE 259(2020):9. |
入库方式： OAI收割
来源：水生生物研究所
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