Background: Schizotypy has been shown to be a time-stable construct that exists across the schizophrenia spectrum. The Multidimensional Schizotypy Scale (MSS) was developed to capture the three factors underlying schizotypy: positive, disorganized and negative schizotypy. However, a recent validation study reported a four-factor construct with an additional negative social anhedonia factor. The factor structure of the Chinese version of the MSS remains unknown. This study aimed to identify and validate the factor structure of the Chinese version of the MSS. Methods: We recruited 641 Chinese speakers via on-line advertisement. We administered the Chinese version of the MSS, which was a self-report instrument. The scale consists of 77 items with true or false response options. We identified and removed 43 outliers. Finally, a total of 294 participants were randomly selected as the derivative sample for exploratory factor analysis (EFA). The remaining 304 participants were retained as the validation sample for confirmatory factor analysis (CFA). Results: EFA identified four factors: the positive factor, the disorganization factor, the negative affective and motivational anhedonia factor, and the negative social anhedonia factor. The EFA-identified four-factor model was compared with the unidimensional, three-factor bifactorial and theoretical three-factor models using CFAs. The three-factor bifactorial model fitted the data better than the EFA-identified four-factor model. Conclusion: Our finding suggests that the Chinese version of the MSS is a valid tool for assessing schizotypy in the Chinese setting.