中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
Systematically lower structural brain connectivity in individuals with elevated food addiction symptoms

文献类型:期刊论文

作者Peng-Li, Danni2,3,4; Sorensen, Thomas Alrik4,6; Li, Yonghui3,5; He, Qinghua1,7,8
刊名APPETITE
出版日期2020-12-01
卷号155页码:10
关键词Diffusion tensor imaging Voxel-based morphometry Yale food addiction scale Decision-making Food reward Interoceptive awareness Individual differences
ISSN号0195-6663
DOI10.1016/j.appet.2020.104850
通讯作者Li, Yonghui(liyonghui@psych.ac.cn) ; He, Qinghua(heqinghua@swu.edu.cn)
英文摘要Symptoms of food addiction have been observed in both obesity and eating disorders. The food addiction model may therefore posit a continuum of dysfunctional personality traits, including increased impulsivity and poor decision-making. The current study explored the neuroanatomy of addictive-like eating behavior from a novel triadic model of addiction. Specifically, we focused on three interacting neural systems; a sensitized impulsive, reward system associated with striatal structures, a desensitized reflective control system governed by prefrontal cortex, and a disrupted insula-mediated interoceptive system responsible for integrating and translating interoceptive, somatic signals into feelings of anticipation, desires, or cravings. Sixty-four healthy-weight Chinese university students were scanned for high-resolution structural and diffusion imaging. Data from the Yale Food Addiction Scale (YFAS), Binge Eating Scale, Eating Attitude Test-26, UPPS-P Impulsive Behavior Scale, and Delay Discounting Task were collected. Based on YFAS-score, participants were divided into a High Food Addiction group (HFA) and a Low Food Addiction group (LFA). Diffusion tensor imaging results revealed that compared to LFA, HFA had lower structural connectivity between insula and anterior cingulate cortex, insula and caudate, and ventromedial Prefrontal Cortex (vmPFC) and putamen. The Voxel-Based Morphometry analysis suggested marginally lower gray matter volume in the left vmPFC in HFA. Finally, behavioral results, indicated that higher food addiction symptoms were associated with personality traits exhibited in eating disorders including impulsive decision-making. These findings suggest that even in a healthy population, some individuals may be more susceptible to develop unhealthy relationships to food, which at least partially is manifested in lower structural connectivity between brain regions associated with interoceptive awareness, decision-making, and reward.
WOS关键词SELF-REPORTED WEIGHT ; BODY-MASS INDEX ; EATING ATTITUDES ; OBESE-PATIENTS ; SAMPLE ; VALIDATION ; INSULA ; IMPULSIVITY ; HEIGHT ; MATTER
资助项目National Natural Science Foundation of China[31972906] ; National Natural Science Foundation of China[U1736124] ; Open Research Fund of the Key Laboratory of Mental Health, Institute of Psychology, Chinese Academy of Sciences[KLMH2019K05] ; National Key Research and Development Program of China[2017YFC1310405] ; CAS Key Lab of Mental Health Project
WOS研究方向Behavioral Sciences ; Nutrition & Dietetics
语种英语
WOS记录号WOS:000573294600002
出版者ACADEMIC PRESS LTD- ELSEVIER SCIENCE LTD
资助机构National Natural Science Foundation of China ; Open Research Fund of the Key Laboratory of Mental Health, Institute of Psychology, Chinese Academy of Sciences ; National Key Research and Development Program of China ; CAS Key Lab of Mental Health Project
源URL[http://ir.psych.ac.cn/handle/311026/32936]  
专题心理研究所_中国科学院心理健康重点实验室
通讯作者Li, Yonghui; He, Qinghua
作者单位1.Southwest Univ, Fac Psychol, Chongqing 400715, Peoples R China
2.Aarhus Univ, Dept Food Sci, Aarhus, Denmark
3.Chinese Acad Sci, Inst Psychol, 16 Lincui Rd, Beijing 100080, Peoples R China
4.Sino Danish Ctr Educ & Res, Beijing, Peoples R China
5.Univ Chinese Acad Sci, Dept Psychol, Beijing, Peoples R China
6.Aalborg Univ, Dept Commun & Psychol, Aalborg, Denmark
7.Chinese Acad Sci, Key Lab Mental Hlth, Beijing, Peoples R China
8.Beijing Normal Univ, Southwest Univ Branch, Collaborat Innovat Ctr Assessment Basic Educ Qual, Chongqing, Peoples R China
推荐引用方式
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Peng-Li, Danni,Sorensen, Thomas Alrik,Li, Yonghui,et al. Systematically lower structural brain connectivity in individuals with elevated food addiction symptoms[J]. APPETITE,2020,155:10.
APA Peng-Li, Danni,Sorensen, Thomas Alrik,Li, Yonghui,&He, Qinghua.(2020).Systematically lower structural brain connectivity in individuals with elevated food addiction symptoms.APPETITE,155,10.
MLA Peng-Li, Danni,et al."Systematically lower structural brain connectivity in individuals with elevated food addiction symptoms".APPETITE 155(2020):10.

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来源:心理研究所

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