Efficient Bond of PDMS and Printed Circuit Board with An Application on Continuous-flow Polymerase Chain Reaction
文献类型：期刊论文
| 作者 | Chang, Yongjia1,2; You, Hui3
|
| 刊名 | BIOCHIP JOURNAL
 |
| 出版日期 | 2020-12-01 |
| 卷号 | 14 |
| 关键词 | Microfluidics PDMS PCB Continuous-flow PCR Bonding |
| ISSN号 | 1976-0280 |
| DOI | 10.1007/s13206-020-4403-0 |
| 通讯作者 | You, Hui(usmlhy@iim.ac.cn) |
| 英文摘要 | A simple and efficient bond technique for integrating polydimethylsiloxane (PDMS) and printed circuit board (PCB) is presented in this paper by using half-cured PDMS technique. We take advantage of the mature PCB technology for fabrication of microchannel mold and heating electrodes leading to a cost-effective and mass manufacturing method. PDMS is applied for fabricating microfluidic chip by replica molding while a seamless and reliable bond is formed between cured PDMS chip and half-cured PDMS film on PCB substrate. To demonstrate the reliability of the system, the bond strengths of the PDMS film to PCB substrate as well as the PDMS chip to PDMS film are investigated. An application of a continuous-flow PCR (CF-PCR) chip is also fabricated based on the bond technique. Successful DNA amplification is obtained and compared to the conventional PCR reaction. The proposed bond method is a promising attempt for the integration between polymer and PCB which can be critical for the microfluidic applications requiring low cost, high efficiency and portability. |
| WOS关键词 | MICROFLUIDIC DEVICES ; PCB ; MICROCHIP ; ADHESIVE ; SILOXANE |
| 资助项目 | Strategic Priority Research Program of the Chinese Academy of Sciences[XDA08040109] ; Young Spark Project Foundation of CASHIPS[YZJJ2020QN19] |
| WOS研究方向 | Biochemistry & Molecular Biology ; Chemistry ; Science & Technology - Other Topics |
| 语种 | 英语 |
| WOS记录号 | WOS:000585781000001 |
| 出版者 | KOREAN BIOCHIP SOCIETY-KBCS |
| 资助机构 | Strategic Priority Research Program of the Chinese Academy of Sciences ; Young Spark Project Foundation of CASHIPS |
| 源URL | [http://ir.hfcas.ac.cn:8080/handle/334002/105250]  |
| 专题 | 中国科学院合肥物质科学研究院 |
| 通讯作者 | You, Hui |
| 作者单位 | 1.Chinese Acad Sci, Inst Intelligent Machines, Hefei 230031, Anhui, Peoples R China 2.Univ Sci & Technol China, Hefei 230026, Anhui, Peoples R China 3.Guangxi Univ, Sch Mech Engn, Nanning 530004, Guangxi, Peoples R China |
| 推荐引用方式 GB/T 7714 | Chang, Yongjia,You, Hui. Efficient Bond of PDMS and Printed Circuit Board with An Application on Continuous-flow Polymerase Chain Reaction[J]. BIOCHIP JOURNAL,2020,14. |
| APA | Chang, Yongjia,&You, Hui.(2020).Efficient Bond of PDMS and Printed Circuit Board with An Application on Continuous-flow Polymerase Chain Reaction.BIOCHIP JOURNAL,14. |
| MLA | Chang, Yongjia,et al."Efficient Bond of PDMS and Printed Circuit Board with An Application on Continuous-flow Polymerase Chain Reaction".BIOCHIP JOURNAL 14(2020). |
入库方式： OAI收割
来源：合肥物质科学研究院
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