Separative extended-gate AlGaAs/GaAs HEMT biosensors based on capacitance change strategy
文献类型：期刊论文
| 作者 | Yu, Jiahuan; Xu, Mengke; Liang, Lingyan; Guan, Min; Zhang, Yang; Yan, Feng; Cao, Hongtao |
| 刊名 | APPLIED PHYSICS LETTERS
 |
| 出版日期 | 2020 |
| 卷号 | 116期号:12 |
| 关键词 | FIELD-EFFECT TRANSISTORS LABEL-FREE CHANNEL |
| DOI | 10.1063/5.0001786 |
| 英文摘要 | Separative extended-gate AlGaAs/GaAs high electron mobility transistor (HEMT) biosensors based on the capacitance change strategy are proposed and fabricated. The working mechanism underlying this strategy is clearly clarified via examining the capacitance evolution on biorecognition and the capacitance matching issue between the HEMT and the sensing pad. The fabricated biosensors demonstrate a good linear current/voltage response to a label-free prostate-specific antigen (PSA) target over a broad concentration range of 100 fg/ml to 10ng/ml in both 0.1x and 1x phosphate buffered saline solutions. Specifically, the sensitivity variation approaches 8.7% dec(-1) at the critical concentration level of 2-8ng/ml that enters the normal PSA region in the human body. The advantages of high sensitivity, low-cost, and convenience of usage make the proposed HEMT biosensors potential candidates for prostate cancer diagnosis. |
| 学科主题 | Physics |
| 源URL | [http://ir.nimte.ac.cn/handle/174433/19859]  |
| 专题 | 2020专题 2020专题_期刊论文 |
| 作者单位 | 1.Liang, LY (corresponding author), Chinese Acad Sci, Div Funct Mat & Nano Devices, Ningbo Inst Mat Technol & Engn, Ningbo 315201, Peoples R China. 2.Zhang, Y (corresponding author), Chinese Acad Sci, Key Lab Semicond Mat Sci, Beijing Key Lab Low Dimens Semicond Mat & Devices, Inst Semicond, Beijing 100083, Peoples R China. 3.Guan, M |
| 推荐引用方式 GB/T 7714 | Yu, Jiahuan,Xu, Mengke,Liang, Lingyan,et al. Separative extended-gate AlGaAs/GaAs HEMT biosensors based on capacitance change strategy[J]. APPLIED PHYSICS LETTERS,2020,116(12). |
| APA | Yu, Jiahuan.,Xu, Mengke.,Liang, Lingyan.,Guan, Min.,Zhang, Yang.,...&Cao, Hongtao.(2020).Separative extended-gate AlGaAs/GaAs HEMT biosensors based on capacitance change strategy.APPLIED PHYSICS LETTERS,116(12). |
| MLA | Yu, Jiahuan,et al."Separative extended-gate AlGaAs/GaAs HEMT biosensors based on capacitance change strategy".APPLIED PHYSICS LETTERS 116.12(2020). |
入库方式： OAI收割
来源：宁波材料技术与工程研究所
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