Soil water and cave drip water from four cave systems in Guizhou, Southwest China, were monitored and sampled monthly from April 2003 to May 2004 to understand spatio-temporal variations in hydro-geochemistry of cave percolation water. The results indicated that among the 5 drip water sites from the Liangfeng Cave (LFC), there were no significant differences among the hydro-geochemical parameters. In the Xiniu Cave (XNC), the drip rates were variable and responded quickly to precipitation events in the 3# (No. 3) drip site with variable water head; both bulk and variation in drip rates were smaller in the 2# with constant water head. However, in the Qixing Cave (QXC) and Jiangjun Cave (JJC), drip rates, concentrations of major ions and saturation index for calcite (SIC) were smaller, and Mg/Ca ratios in Group I (1#, 2#, 6#, 7# and 8# in the QXC; 2# and 3# in the JJC) were larger than those in Group II (3#, 4#, 5# and 9# in the QXC; 1# and 4# in the JJC). These differences might be the result of different hydrogeological processes above the caves, which are divided into five categories based on hydro-geochemistry data. The formation of some proxies in speleothem, such as Mg/Ca, is likely to be affected by those processes.