Hierarchy of Connectivity-Function Relationship of the Human Cortex Revealed through Predicting Activity across Functional Domains
文献类型：期刊论文
| 作者 | Wu, Dongya1,6,7,8 ; Fan, Lingzhong5,6,7,8; Song, Ming7,8; Wang, Haiyan6,7,8; Chu, Congying7,8; Yu, Shan6,7,8; Jiang, Tianzi2,3,4,5,6,7,8
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| 刊名 | CEREBRAL CORTEX
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| 出版日期 | 2020-08-01 |
| 卷号 | 30期号:8页码:4607-4616 |
| 关键词 | anatomical connectivity dMRI fMRI functional activations prediction |
| ISSN号 | 1047-3211 |
| DOI | 10.1093/cercor/bhaa063 |
| 通讯作者 | Jiang, Tianzi(jiangtz@nlpr.ia.ac.cn) |
| 英文摘要 | Many studies showed that anatomical connectivity supports both anatomical and functional hierarchies that span across the primary and association cortices in the cerebral cortex. Even though a structure-function relationship has been indicated to uncouple in the association cortex, it is still unknown whether anatomical connectivity can predict functional activations to the same degree throughout the cortex, and it remains unclear whether a hierarchy of this connectivity-function relationship (CFR) exists across the human cortex. We first addressed whether anatomical connectivity could be used to predict functional activations across different functional domains using multilinear regression models. Then, we characterized the CFR by predicting activity from anatomical connectivity throughout the cortex. We found that there is a hierarchy of CFR between sensory-motor and association cortices. Moreover, this CFR hierarchy was correlated to the functional and anatomical hierarchies, respectively, reflected in functional flexibility and the myelin map. Our results suggest a shared hierarchical mechanism in the cortex, a finding which provides important insights into the anatomical and functional organizations of the human brain. |
| WOS关键词 | INDIVIDUAL-DIFFERENCES ; DIFFUSION MRI ; HUMAN BRAIN ; PARCELLATION ; FMRI ; TRACTOGRAPHY ; GRADIENTS ; COGNITION ; NETWORKS ; ATLAS |
| 资助项目 | Natural Science Foundation of China[91432302] ; Natural Science Foundation of China[31620103905] ; Natural Science Foundation of China[81501179] ; Science Frontier Program of the Chinese Academy of Sciences[QYZDJ-SSW-SMC019] ; National Key R&D Program of China[2017YFA0105203] ; Beijing Municipal Science & Technology Commission[Z161100000216152] ; Beijing Municipal Science & Technology Commission[Z181100001518004] ; Beijing Municipal Science & Technology Commission[Z171100000117002] ; Guangdong Pearl River Talents Plan[2016ZT06S220] |
| WOS研究方向 | Neurosciences & Neurology |
| 语种 | 英语 |
| WOS记录号 | WOS:000562454500023 |
| 出版者 | OXFORD UNIV PRESS INC |
| 资助机构 | Natural Science Foundation of China ; Science Frontier Program of the Chinese Academy of Sciences ; National Key R&D Program of China ; Beijing Municipal Science & Technology Commission ; Guangdong Pearl River Talents Plan |
| 源URL | [http://ir.ia.ac.cn/handle/173211/40511]  |
| 专题 | 自动化研究所_脑网络组研究中心 |
| 通讯作者 | Jiang, Tianzi |
| 作者单位 | 1.Northwest Univ, Sch Informat Sci & Technol, Xian 710069, Peoples R China 2.Chinese Inst Brain Res, Beijing 102206, Peoples R China 3.Univ Queensland, Queensland Brain Inst, Brisbane, Qld 4072, Australia 4.Univ Elect Sci & Technol China, Chengdu Brain Sci Inst, MOE Key Lab Neuroinformat, Clin Hosp, Chengdu 625014, Peoples R China 5.Chinese Acad Sci, CAS Ctr Excellence Brain Sci & Intelligence Techn, Inst Automat, Beijing 100190, Peoples R China 6.Univ Chinese Acad Sci, Beijing 100049, Peoples R China 7.Chinese Acad Sci, Inst Automat, Natl Lab Pattern Recognit, Beijing 100190, Peoples R China 8.Chinese Acad Sci, Brainnetome Ctr, Inst Automat, Beijing 100190, Peoples R China |
| 推荐引用方式 GB/T 7714 | Wu, Dongya,Fan, Lingzhong,Song, Ming,et al. Hierarchy of Connectivity-Function Relationship of the Human Cortex Revealed through Predicting Activity across Functional Domains[J]. CEREBRAL CORTEX,2020,30(8):4607-4616. |
| APA | Wu, Dongya.,Fan, Lingzhong.,Song, Ming.,Wang, Haiyan.,Chu, Congying.,...&Jiang, Tianzi.(2020).Hierarchy of Connectivity-Function Relationship of the Human Cortex Revealed through Predicting Activity across Functional Domains.CEREBRAL CORTEX,30(8),4607-4616. |
| MLA | Wu, Dongya,et al."Hierarchy of Connectivity-Function Relationship of the Human Cortex Revealed through Predicting Activity across Functional Domains".CEREBRAL CORTEX 30.8(2020):4607-4616. |
入库方式： OAI收割
来源：自动化研究所
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