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Computational Investigation of Contributions from Different Subtypes of Interneurons in Prefrontal Cortex for Information Maintenance

文献类型：期刊论文

作者Zhang, Qian1,2; Zeng, Yi1,2,3,4; Yang, Taoyi1
刊名SCIENTIFIC REPORTS
出版日期2020-03-13
卷号10期号:1页码:9
ISSN号2045-2322
DOI10.1038/s41598-020-61647-2
通讯作者Zhang, Qian(q.zhang@ia.ac.cn) ; Zeng, Yi(yi.zeng@ia.ac.cn)
英文摘要Interneurons play crucial roles in neocortex associated with high-level cognitive functions; however, the specific division of labor is still under investigation. Interneurons are exceptionally diverse in their morphological appearance and functional properties. In this study, we modify a prefrontal multicolumn circuit in which five subtypes of inhibitory interneurons play distinct roles in the maintenance of transient information. These interneurons are classified according to the extending range of axonal projections. Our work simplifies the division of labor between different types of interneurons for the maintenance of information and the principle of functional redundancy of the brain from the perspective of computational modeling. This model presents a framework to understand the cooperation between different interneurons in a recurrent cortical circuit.
WOS关键词INHIBITORY NEURONS ; PYRAMIDAL NEURON ; ORGANIZATION ; MODEL ; SUBNETWORKS ; CONNECTIONS ; COLUMNAR ; RELEASE ; AXON ; RAT
资助项目Key Research Program of Frontier Sciences, CAS[ZDBS-LY-JSC013] ; Brain-inspired Cognition of Consciousness and Anesthesia[Y8D1051LE1] ; National Natural Science Foundation of China[81501594] ; Strategic Priority Research Program of Chinese Academy of Sciences[XDB32070100] ; Beijing Municipality of Science and Technology[Z181100001518006] ; Major Research Program of Shandong Province[2018CXGC1503]
WOS研究方向Science & Technology - Other Topics
语种英语
WOS记录号WOS:000563437800007
出版者NATURE PUBLISHING GROUP
资助机构Key Research Program of Frontier Sciences, CAS ; Brain-inspired Cognition of Consciousness and Anesthesia ; National Natural Science Foundation of China ; Strategic Priority Research Program of Chinese Academy of Sciences ; Beijing Municipality of Science and Technology ; Major Research Program of Shandong Province
源URL[http://ir.ia.ac.cn/handle/173211/40542]  
专题类脑智能研究中心_类脑认知计算
通讯作者Zhang, Qian; Zeng, Yi
作者单位1.Chinese Acad Sci, Res Ctr Brain Inspired Intelligence, Inst Automat, Beijing 100049, Peoples R China
2.Univ Chinese Acad Sci, Beijing 100049, Peoples R China
3.Chinese Acad Sci, Ctr Excellence Brain Sci & Intelligence Technol, Shanghai 200031, Peoples R China
4.Chinese Acad Sci, Inst Automat, Natl Lab Pattern Recognit, Beijing 100190, Peoples R China
推荐引用方式
GB/T 7714		 Zhang, Qian,Zeng, Yi,Yang, Taoyi. Computational Investigation of Contributions from Different Subtypes of Interneurons in Prefrontal Cortex for Information Maintenance[J]. SCIENTIFIC REPORTS,2020,10(1):9.
APA Zhang, Qian,Zeng, Yi,&Yang, Taoyi.(2020).Computational Investigation of Contributions from Different Subtypes of Interneurons in Prefrontal Cortex for Information Maintenance.SCIENTIFIC REPORTS,10(1),9.
MLA Zhang, Qian,et al."Computational Investigation of Contributions from Different Subtypes of Interneurons in Prefrontal Cortex for Information Maintenance".SCIENTIFIC REPORTS 10.1(2020):9.

入库方式： OAI收割

来源：自动化研究所

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