What Are the Major Physicochemical Factors in Determining the Preferential Nuclear Uptake of the DNA Light-Switching Ru(II)-Polypyridyl Complex in Live Cells via Ion-Pairing with Chlorophenolate Counter-Anions?
文献类型：期刊论文
| 作者 | Huang, Rong; Tang, Miao; Huang, Chun-Hua; Chao, Xi-Juan; Yan, Zhu-Ying; Shao, Jie; Zhu, Ben-Zhan |
| 刊名 | JOURNAL OF PHYSICAL CHEMISTRY LETTERS
 |
| 出版日期 | 2019-07-18 |
| 卷号 | 10期号:14页码:4123-4128 |
| ISSN号 | 1948-7185 |
| 英文摘要 | Delivering potential theranostic metal complexes into preferential cellular targets is becoming of increasing interest. Here we report that nuclear uptake of a cell-impermeable DNA light-switching Ru(II)-polypyridyl complex can be significantly facilitated by chlorophenolate counter-anions, which was found, unexpectedly, to be correlated positively with the binding stability but inversely with the lipophilicity of the formed ion pairs. |
| 源URL | [http://ir.rcees.ac.cn/handle/311016/42613]  |
| 专题 | 生态环境研究中心_环境化学与生态毒理学国家重点实验室 |
| 作者单位 | 1.Res Ctr Ecoenvironm Sci, State Key Lab Environm Chem & Ecotoxicol, Beijing 100085, Peoples R China 2.[Huang, Rong 3.Tang, Miao 4.Huang, Chun-Hua 5.Chao, Xi-Juan 6.Yan, Zhu-Ying 7.Shao, Jie 8.Univ Chinese Acad Sci, Chinese Acad Sci, Beijing 100085, Peoples R China 9.Lanzhou Univ, Sch Life Sci, Lanzhou 730000, Gansu, Peoples R China 10.Oregon State Univ, Linus Pauling Inst, Corvallis, OR 97331 USA |
| 推荐引用方式 GB/T 7714 | Huang, Rong,Tang, Miao,Huang, Chun-Hua,et al. What Are the Major Physicochemical Factors in Determining the Preferential Nuclear Uptake of the DNA Light-Switching Ru(II)-Polypyridyl Complex in Live Cells via Ion-Pairing with Chlorophenolate Counter-Anions?[J]. JOURNAL OF PHYSICAL CHEMISTRY LETTERS,2019,10(14):4123-4128. |
| APA | Huang, Rong.,Tang, Miao.,Huang, Chun-Hua.,Chao, Xi-Juan.,Yan, Zhu-Ying.,...&Zhu, Ben-Zhan.(2019).What Are the Major Physicochemical Factors in Determining the Preferential Nuclear Uptake of the DNA Light-Switching Ru(II)-Polypyridyl Complex in Live Cells via Ion-Pairing with Chlorophenolate Counter-Anions?.JOURNAL OF PHYSICAL CHEMISTRY LETTERS,10(14),4123-4128. |
| MLA | Huang, Rong,et al."What Are the Major Physicochemical Factors in Determining the Preferential Nuclear Uptake of the DNA Light-Switching Ru(II)-Polypyridyl Complex in Live Cells via Ion-Pairing with Chlorophenolate Counter-Anions?".JOURNAL OF PHYSICAL CHEMISTRY LETTERS 10.14(2019):4123-4128. |
入库方式： OAI收割
来源：生态环境研究中心
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