Spatially Explicit Large-Scale Environmental Risk Assessment of Pharmaceuticals in Surface Water in China
文献类型：期刊论文
| 作者 | Zhu, Ying; Snape, Jason; Jones, Kevin; Sweetman, Andrew |
| 刊名 | ENVIRONMENTAL SCIENCE & TECHNOLOGY
 |
| 出版日期 | 2019-03-05 |
| 卷号 | 53期号:5页码:2559-2569 |
| ISSN号 | 0013-936X |
| 英文摘要 | With improving healthcare and an aging population, the consumption of human pharmaceuticals in China has been increasing dramatically. Environmental risks posed by many active pharmaceutical ingredients (APIs) are still unknown. This study used a spatially explicit dilution-factor methodology to model predicted environmental concentrations (PECs) of 11 human-use APIs in surface water for a preliminary environmental risk assessment (ERA). Median PECs in surface water across China range between 0.01 and 8.0 x 103 ng/L for the different APIs, under a moderate patient use scenario. Higher environmental risks of APIs in surface water are in regions with high water stress, e.g., northern China. Levonorgestrel, estradiol, ethinyl estradiol and abiraterone acetate were predicted to potentially pose a high or moderate environmental risk in China if consumption levels reach those in Europe. Relative risks of these four APIs have the potential to be among those chemicals with the highest impact on surface water in China when compared to the risks associated with other regulated chemicals, including triclosan and some standard water quality parameters including BODs (5-day biological oxygen demand), COD (chemical oxygen demand), Cu, Zn, and Hg and linear alkylbenzene sulfonate. This method could support the regulation of this category of chemicals and risk mitigation strategies in China. |
| 源URL | [http://ir.rcees.ac.cn/handle/311016/43020]  |
| 专题 | 生态环境研究中心_环境化学与生态毒理学国家重点实验室 |
| 作者单位 | 1.Univ Lancaster, Lancaster Environm Ctr, Lancaster LA1 4YQ, England 2.AstraZeneca, Global Safety Hlth & Environm, Alderley Pk, Macclesfield SK10 4TG, Cheshire, England 3.Univ Warwick, Sch Life Sci, Gibbet Hill Campus, Coventry CV4 7AL, W Midlands, England 4.Chinese Acad Sci, Res Ctr Ecoenvironm Sci, State Key Lab Environm Chem & Ecotoxicol, Beijing 100085, Peoples R China |
| 推荐引用方式 GB/T 7714 | Zhu, Ying,Snape, Jason,Jones, Kevin,et al. Spatially Explicit Large-Scale Environmental Risk Assessment of Pharmaceuticals in Surface Water in China[J]. ENVIRONMENTAL SCIENCE & TECHNOLOGY,2019,53(5):2559-2569. |
| APA | Zhu, Ying,Snape, Jason,Jones, Kevin,&Sweetman, Andrew.(2019).Spatially Explicit Large-Scale Environmental Risk Assessment of Pharmaceuticals in Surface Water in China.ENVIRONMENTAL SCIENCE & TECHNOLOGY,53(5),2559-2569. |
| MLA | Zhu, Ying,et al."Spatially Explicit Large-Scale Environmental Risk Assessment of Pharmaceuticals in Surface Water in China".ENVIRONMENTAL SCIENCE & TECHNOLOGY 53.5(2019):2559-2569. |
入库方式： OAI收割
来源：生态环境研究中心
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